Cribra orbitalia, a possible sign of anemia in early historic native populations of the British Columbia Coast.
Cribra orbitalia, a possible sign of anemia in early historic native populations of the British Columbia Coast.
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Cribra 眼眶，是不列颠哥伦比亚省海岸早期历史原住民贫血的可能迹象。
DOI：
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发表时间：
1977
影响因子：
2.8
通讯作者：
J. Cybulski
中科院分区：
文献类型：
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作者：
J. Cybulski
接触后时期的出土和博物馆骨骼揭示了不列颠哥伦比亚省海岸的四个本土民族语言区（海达、夸奎特尔、努特卡和萨利什海岸）的克里布拉眼眶。受影响的头骨分布在 35 个地点中的 25 个地区，表明在主要异质人群中广泛发生。表现与多孔性骨质增生相似，样本中的其他病变倾向于支持筛眼眶与贫血相关的概念。遗传性和获得性疾病都可能与病因有关。 52.9%的独特高发病率发生在海达族的未成熟群体中，这是一个相对同质的群体。然而，总样本中不同年龄组和性别的表达存在显着差异，提示缺铁性贫血。数据和历史信息与现代对易感性的预期一致。在 454 个头骨中，32.7% 的成长儿童和青少年、19% 的婴儿和幼儿、13.3% 的成年女性和 4.8% 的成年男性出现眼眶畸形。接触后的干扰和疾病可能会促进缺铁性贫血，但注意到接触前的情况也可能是由这种疾病引起的。
Excavated and museum skeletons of the postcontact period revealed cribra orbitalia in four native ethnolinguistic divisions of the British Columbia coast, Haida, Kwakiutl, Nootka, and Coast Salish. Affected skulls were distributed among 25 of 35 localities, indicating widespread occurrence in a mainly heterogeneous population. Manifestations were similar to porotic hyperostosis, and additional lesions in the sample tend to support the concept that cribra orbitalia is related to anemia. Both inherited and acquired disorders may have been involved in the etiology. A uniquely high incidence of 52.9% occurred in immature of the Haida, a relatively homogeneous population. However, marked variability in expression by age group and by sex in the total sample is suggestive of iron-deficiency anemia. The data and historical information parallel modern expectations of susceptibility. Among 454 skulls, criba orbitalia occurred in 32.7% of growing children and adolescents, 19% of infants and toddlers, 13.3% of adult females, and 4.8% of adult males. Postcontact disruptions and disease may have figured in promoting iron-deficiency anemia, but noted precontact occurrences may also have been due to the disorder.