Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis: A study with tractography and diffusion-tensor imaging
Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis: A study with tractography and diffusion-tensor imaging
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DOI：
10.3109/17482960802651717
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发表时间：
2009-01-01
影响因子：
--
通讯作者：
Sobue, Gen
中科院分区：
文献类型：
--
作者：
Senda, Joe;Ito, Mizuki;Sobue, Gen
我们的目的是利用弥散张量磁共振成像（DTI）评估肌萎缩侧索硬化（ALS）患者白色受累的位置和范围。我们从46例散发性ALS患者和19例对照组的内囊和各种白色物质区域获得了各向异性分数（FA）值。在ALS患者中，内囊、额部白色物质、胼胝体压部和胼胝体前部的FA值（p
Our aim was to evaluate the location and extent of white matter involvement in patients with amyotrophic lateral sclerosis (ALS) using diffusion-tensor magnetic resonance imaging (DTI). We obtained fractional anisotropy (FA) values from the internal capsule and various white matter regions of 46 patients with sporadic ALS and 19 control subjects. In ALS patients, FA values in the internal capsule, frontal white matter, genu and splenium of the corpus callosum (p