A PROSPECTIVE-STUDY OF EXERCISE AND INCIDENCE OF DIABETES AMONG UNITED-STATES MALE PHYSICIANS
A PROSPECTIVE-STUDY OF EXERCISE AND INCIDENCE OF DIABETES AMONG UNITED-STATES MALE PHYSICIANS
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DOI：
10.1001/jama.268.1.63
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发表时间：
1992-07-01
影响因子：
120.7
通讯作者：
HENNEKENS, CH
中科院分区：
文献类型：
--
作者：
MANSON, JE;NATHAN, DM;HENNEKENS, CH
客观。-前瞻性地研究规律运动与非胰岛素依赖型糖尿病（NIDDM）的发生之间的关系。前瞻性队列研究，包括5年的随访。21 271名参与医生健康研究的美国男性医生，年龄40至84岁，基线时未诊断出糖尿病、心肌梗死、脑血管疾病和癌症。随访完成率为99.7%。主要结果指标。NIDDM的发病率.结果. -在基线时，获得有关剧烈运动频率和其他风险指标的信息。在105141人年的随访期间，报告了285例新的NIDDM病例。年龄调整后的NIDDM发病率范围从每周剧烈运动少于一次的男性每10万人年369例到每周运动至少五次的男性每10万人年214例（P，趋势，
Objective.-To examine prospectively the association between regular exercise and the subsequent development of non-insulin-dependent diabetes mellitus (NIDDM).Design.-Prospective cohort study including 5 years of follow-up.Participants.-21 271 US male physicians participating in the Physicians' Health Study, aged 40 to 84 years and free of diagnosed diabetes mellitus, myocardial infarction, cerebrovascular disease, and cancer at baseline. Morbidity follow-up was 99.7% complete.Main Outcome Measure.-Incidence of NIDDM.Results.-At baseline, information was obtained about frequency of vigorous exercise and other risk indicators. During 105 141 person-years of follow-up, 285 new cases of NIDDM were reported. The age-adjusted incidence of NIDDM ranged from 369 cases per 1 00 000 person-years in men who engaged in vigorous exercise less than once weekly to 214 cases per 1 00 000 person-years in those exercising at least five times per week (P, trend,