Eosinophilic Esophagitis: Another Atopy-Related Alopecia Areata Trigger?
Eosinophilic Esophagitis: Another Atopy-Related Alopecia Areata Trigger?
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嗜酸性粒细胞性食管炎：另一种与特应性相关的斑秃触发因素？
DOI：
10.1038/jidsymp.2015.43
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Piliang,Melissa
中科院分区：
文献类型：
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作者：
Ibrahim,Omer;Bergfeld,WilmaF;Piliang,Melissa
斑秃（AA）在10-22%的患者中与特应性相关，是普通人群患病率的两倍。患者可伴有特应性皮炎、花粉热、哮喘，甚至对尘螨过敏。在许多情况下，这些特应性疾病的严重程度和发作与AA的严重程度相关。我们在此报告一例AA合并同时性嗜酸性食管炎（EoE）的患者。EoE是最近发现的一种过敏性疾病，由嗜酸性粒细胞和组胺介导。其特征是食管功能障碍和上皮内微脓肿。我们建议将EoE视为属于特应性疾病领域的一种情况，并且是受影响患者AA的潜在触发因素。
Alopecia areata (AA) is associated with atopy in 10–22% of patients, twice the prevalence in the general population. Patients can present with concomitant atopic dermatitis, hay fever, asthma, and even allergies to dust mites. In many cases, severity and flares of these atopic diatheses correlate with severity of AA. Herein we present a patient with AA affected by contemporaneous eosinophilic esophagitis (EoE). EoE is a recently recognized allergic disorder, mediated by eosiniphils and histamine. It is characterized by esophageal dysfunction and intraepithelial microabscesses. We propose that EoE be considered as a condition falling within the realm of atopic diseases, and a potential trigger of AA in affected patients.