Psychosis risk syndrome is not prodromal psychosis.
Psychosis risk syndrome is not prodromal psychosis.
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精神病风险综合征不是前驱精神病。
DOI：
10.11919/j.issn.1002-0829.214178
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发表时间：
2015-02-25
期刊：
影响因子：
--
通讯作者：
Wang J
中科院分区：
文献类型：
--
作者：
Xu L;Zhang T;Wang J
精神分裂症研究中最令人兴奋的趋势之一是将重点从治疗研究转向精神分裂症的早期识别和预防研究。这些研究主要集中在有前驱症状的青少年或青壮年或临床高危个体，这些个体在认知和社会功能方面表现出与精神分裂症患者相似的损伤，因此被认为具有患精神分裂症或其他精神障碍的高风险。一些研究者将这种情况称为精神病风险综合征（PRS）。在一些圈子里，有人将这种情况重新定义为一种独立的疾病：美国精神病学协会的《精神疾病诊断与统计手册》第5版（DSM-5）在附录中将“减重精神病综合征”（APS）列为一种需要进一步研究的疾病。有PRS的个体当然比没有PRS的个体有更高的发展为精神障碍的风险，但大多数有PRS的人随后并没有发展为精神障碍，因此我们反对将PRS或APS作为精神分裂症谱系障碍的亚型。
One of the most exciting trends in schizophrenia research is the shift in focus from treatment studies to studies about the early identification and prevention of schizophrenia. These studies have primarily focused on adolescents or young adults with prodromal symptoms or on clinically high-risk individuals who show similar impairments in cognitive and social functioning to those seen in individuals with schizophrenia and, thus, are considered at high risk of developing schizophrenia or other psychotic disorders. Some researchers have labeled this condition as psychosis risk syndrome (PRS). There are moves in some circles to re-define the condition as a disorder in its own right: the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5), lists ‘attenuated psychosis syndrome’ (APS) in the appendix as a condition for further study. Individuals with PRS are certainly at higher risk of developing a psychotic disorder than those without PRS, but the majority of those with PRS do not subsequently develop a psychotic disorder, so we argue against the inclusion of PRS or APS as a subtype of schizophrenia spectrum disorder.