CLASSIC: Consistent longitudinal alignment and segmentation for serial image computing
CLASSIC: Consistent longitudinal alignment and segmentation for serial image computing
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DOI:
10.1016/j.neuroimage.2005.09.054
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发表时间:
2006-04-01
期刊:
影响因子:
5.7
通讯作者:
Davatzikos, C
中科院分区:
文献类型:
--
作者:
Xue, Z;Shen, DG;Davatzikos, C
This paper proposes a temporally consistent and spatially adaptive longitudinal MR brain image segmentation algorithm, referred to as CLASSIC, which aims at obtaining accurate measurements of rates of change of regional and global brain volumes front serial MR images. The algorithm incorporates image-adaptive clustering, spatiotemporal smoothness constraints, and image warping to jointly segment a series of 3-D MR brain images of the same subject that might be undergoing changes due to development, aging, or disease. Morphological changes, such as growth or atrophy, are also estimated as part of the algorithm. Experimental results on simulated and real longitudinal MR brain images show both segmentation accuracy and longitudinal consistency. (c) 2005 Elsevier Inc. All rights reserved.