Motoneuron resting potentials in spinal shock.
Motoneuron resting potentials in spinal shock.
复制标题
脊髓休克中的运动神经元静息电位。
DOI：
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发表时间：
1962
影响因子：
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通讯作者：
B. A. Schottelius
中科院分区：
文献类型：
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作者：
C. Barnes;R. Joynt;B. A. Schottelius
测定猫脊髓功能阻断前、中、后脊髓腰段细胞的静息膜电位。阻断是通过在胸中水平的脐带周围的铜管用o C盐水冷却来实现的。在逆行刺激可识别为运动神经元的单位中，95%在脊髓阻断时经历了2~6 mV(平均3.6±.2 mV)的超极化。一组不能识别为运动神经元的单位发生了2~8 mV的超极化，平均3.7±0.5 mV。脊髓休克的生理性紊乱是运动神经元的超极化。这种超极化被认为是由于神经末梢移除了随机突触的轰击，神经末梢直接或间接从更多的头侧区域激活，这通常会使细胞处于轻微的低极化状态。
The resting membrane potential of cells in the lumbar segment of the spinal cord was measured in cats before, during, and after the cord was functionally blocked. Blocking was achieved by cooling with o C brine passed through a copper tube surrounding the cord at the midthoracic level. Of those units identifiable by antidromic stimulation as motoneurons, 95% underwent a hyperpolarization of from 2 to 6 mv (mean 3.6 ± .2 mv) when the cord was blocked. A group of units that could not be identified as motoneurons underwent a hyperpolarization of from 2 to 8 mv (mean 3.7 ± .5 mv). The physiologic derangement in spinal shock is a hyperpolarization of motoneurons. Such hyperpolarization is thought to result from the removal of random synaptic bombardment by nerve endings, either directly or indirectly activated from more cephalad regions, which normally keep the cell in a slightly hypopolarized state.