NEUROHORMONAL PROPERTIES OF ROYAL JELLY

NEUROHORMONAL PROPERTIES OF ROYAL JELLY
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DOI:
10.1038/188854a0
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发表时间:
1960-01-01
期刊:
影响因子:
64.8
通讯作者:
SMITH, MV
SMITH, MV
中科院分区:
综合性期刊1区
文献类型:
--
作者:
COLHOUN, EH;SMITH, MV

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皇家浆在蜜蜂的多态性发育中具有重要意义。蜜蜂幼虫吃了过量的皇家浆,发育成蜂后;那些吃了数量和质量不同的食物的蜜蜂就成了工蜂。皇家果冻还有其他有趣的特性,因为已有证据表明它对可移植的小鼠白血病有治疗价值2,并存在抗肿瘤作用3。这些效应可以被称为抗生长特性。值得注意的是,据说皇家浆中含有乙酰胆碱,其含量经计算约为昆虫大脑中乙酰胆碱含量的六倍。关于皇家浆中乙酰胆碱的来源,以及这种物质是否含有乙酰胆碱,人们都一无所知,而这种物质是从亨施勒所用的蜜蜂以外的蜜蜂那里获得的。皇家浆中神经激素的出现引起了相当大的兴趣,因为它表明乙酰胆碱可能具有与神经传递相关的功能不同的功能。
ROYAL jelly has significance in polymorphic development of bees. Bee larvæ fed on an overabundance of royal jelly develop into queens ; those given food differing quantitatively and qualitatively become worker bees1. Royal jelly has other interesting properties, for evidence is available of its therapeutic value in transplantable mouse leukæmia2and of the presence of an antibiotic3. These effects might be termed anti-growth properties. It is remarkable that royal jelly is stated to contain acetylcholine4in an amount calculated to be about six times that found in the brain of insects5. Nothing is known about the origin of acetylcholine in royal jelly or indeed whether this substance, obtainable from bees other than those used by Henschler4, contains acetylcholine. The occurrence of a neurohormone in royal jelly is of considerable interest for it suggests that acetylcholine may have a function different from that associated with nervous transmission.