Cell division from a genetic perspective.
Cell division from a genetic perspective.
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DOI：
10.1083/jcb.77.3.627
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发表时间：
1978-06
影响因子：
7.8
通讯作者：
Hartwell, L H
中科院分区：
文献类型：
--
作者：
Hartwell, L H
随着从微生物基因调控和噬菌体形态发生研究中借用的遗传策略被应用于细胞分裂过程，真核细胞周期的新观点正在形成。它是一种基因构建体，其中突变损伤识别主要事件，不耐热基因产物揭示时间顺序，突变表型产生因果关系途径，而调节事件位于基因控制步骤的序列内。
A novel view of the eukaryotic cell cycle is taking form as genetic strategies borrowed from investigations of microbial gene regulation and bacteriophage morphogenesis are being applied to the process of cell division. It is a genetic construct in which mutational lesions identify the primary events, thermolabile gene products reveal temporal order, mutant phenotypes yield pathways of causality, and regulatory events are localized within sequences of gene controlled steps.