Rickettsiosis in Japan.

Rickettsiosis in Japan.
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日本立克次体病。

DOI:
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发表时间:
1988
期刊:
The Japanese journal of experimental medicine
影响因子:
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通讯作者:
H. Tanaka
H. Tanaka
中科院分区:
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文献类型:
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作者:
Akiyoshi Kawamura;H. Tanaka

文献摘要

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日本的立克次体疾病包括恙虫病(恙虫病)、鼠斑疹伤寒(散发)和斑点热群疾病之一(1984年以来被确认为一种新疾病)。从1976年开始,日本的恙虫病报告病例数在经历了几年的实际消失后出现了显著的回升,地方病在1984年达到显著爆发后仍在继续。1982 ~ 1986年的年发病率分别为538例、749例、971例、890例和738例。这种复苏很可能与携带恙虫病立克次体的媒介螨群增加有关。然而,无法解释这些病媒螨聚集区是如何发展的。斑点热群病的存在直到最近才被认识到。这种立克次体病于1984年在德岛和高知县首次发现。迄今为止,估计血清反应阳性病例总数超过45例。使用细胞培养方法从5名患者的血液中分离出致病性立克次体,目前正在对这些立克次体进行鉴定。
The rickettsial diseases of man in Japan include Tsutsugamushi disease (scrub typhus), murine typhus, which occurs sporadically, and one of spotted fever group diseases, recognized as a new entity since 1984. Starting from 1976, there has been a remarkable resurgence in the number of reported cases of Tsutsugamushi disease in Japan after several years of virtual absence, and endemics are still continuing after reaching a prominent outbreak in 1984. Its yearly incidences from 1982 to 1986 were 538, 749, 971, 890 and 738, respectively. This resurgence is most likely related to an increase of vector mite colonies that carry Rickettsia tsutsugamushi. However, it cannot be explained as to how these foci of vector mites developed. The existence of spotted fever group disease had not been recognized until quite recently. This rickettsiosis was first identified in Tokushima and Kochi Prefectures in 1984. To date, the estimated total number of sero-positive cases is over 45 cases. The causative rickettsiae were isolated from the blood of 5 patients using cell culture methods and the identification of these rickettsiae is now being carried out.