The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation.
The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation.
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DOI：
10.1210/edrv.20.4.0373
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发表时间：
1999-08
影响因子：
20.3
通讯作者：
R. Pestell;C. Albanese;A. Reutens;J. Segall;Richard J. Lee;A. Arnold
中科院分区：
文献类型：
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作者：
R. Pestell;C. Albanese;A. Reutens;J. Segall;Richard J. Lee;A. Arnold
一、简介 二．细胞周期 G1 阶段的调节 A. 细胞周期蛋白 B. Cdk 抑制蛋白 C. 细胞周期控制蛋白的转录调节 III．细胞周期蛋白和 Cdk 调节蛋白的内分泌调节 A. 单跨膜片段受体 B. 七次跨膜受体 C. 类固醇激素 D. 细胞内第二信使 IV．内分泌肿瘤中的细胞周期蛋白和 CKI A. 甲状旁腺腺瘤 B. 甲状腺癌 C. 垂体肿瘤 D. 肾上腺肿瘤 E. 卵巢和睾丸癌 F. 细胞周期蛋白 D1 的致癌转化机制 G. CKI 治疗内分泌疾病 V. 调节细胞周期的转录因子 VI.结论
I. Introduction II. Regulation of the Cell Cycle G1 Phase A. The cyclins B. The Cdk-inhibitory proteins C. Regulation of transcription by cell cycle-control proteins III. Endocrine Regulation of Cyclin and Cdk-Regulatory Proteins A. Single-transmembrane segment receptors B. Seven-transmembrane receptors C. Steroid hormones D. Intracellular second messengers IV. Cyclins and CKIs in Endocrine Tumors A. Parathyroid adenomas B. Thyroid cancer C. Pituitary tumors D. Adrenal tumors E. Ovarian and testicular cancer F. Mechanisms of oncogenic transformation by cyclin D1 G. CKIs in treatment of endocrine disease V. Transcription Factors Regulating the Cell Cycle VI. Conclusion