Transcranial magnetic stimulation for migraine: clinical effects.
Transcranial magnetic stimulation for migraine: clinical effects.
复制标题
DOI：
10.1007/s10194-006-0329-8
复制
发表时间：
2006-10
影响因子：
7.4
通讯作者：
Castellanos, Claudia M
中科院分区：
文献类型：
--
作者：
Clarke, Beverley M;Upton, Adrian R M;Kamath, Mark V;Al-Harbi, Talal;Castellanos, Claudia M
目的是评估经颅磁刺激 (TMS) 对偏头痛疼痛和自主神经系统 (ANS) 的影响。 42 人[平均年龄 41.43±11.69 (SD) 岁，36 名女性]被随机分为高 TMS 刺激组和低 TMS 刺激组，并接受 2 次短暂的 TMS 脉冲。三十三 (33/42) 个人在刺激前后评估了心率变异性。没有发现群体效应。疼痛减轻75%； 32% 的人在接受 1 次治疗后 24 小时后没有出现头痛。平均心率从 79.05±10.27 次/分钟下降至 72.89±11.35 次/分钟。功率谱分析得出的低频 (LF) 和高频 (HF) 区域增加[平均 6522±1277 至 8315±1009 次/分钟 (LF) (p=0.001)，平均 5600±1568 至 8755±3071 次/分钟 (HF) (p=0.001)]。 LF:HF 比率从平均 1.31±0.51 下降至 1.13±0.48 (NS)。 TMS 可立即、持续地减轻疼痛并改善 ANS。
The objective was to assess the impact of transcranial magnetic stimulation (TMS) on pain and the autonomic nervous system (ANS) in migraine. Fortytwo people [mean age 41.43±11.69 (SD) years, 36 females] were randomised into high vs. low TMS stimulation groups and received 2 brief pulses of TMS. Thirty-three (33/42) individuals had heart-rate variability assessed, before and after stimulation. No group effects were found. Pain decreased by 75%; 32% of people after 1 treatment reported no headache after 24 h. Mean heart rate decreased from 79.05±10.27 to 72.89±11.35 beats/min. The low-frequency (LF) and the high-frequency (HF) areas derived from power spectral analyses increased [mean 6522±1277 to 8315±1009 beats/min2 (LF) (p=0.001) and mean 5600±1568 to 8755±3071 beats/min2 (HF) (p=0.001)]. The LF:HF ratio decreased from mean 1.31±0.51 to 1.13±0.48 (NS). TMS produces immediate, sustained reductions in pain and modification of the ANS.