Rhodococcus equi: An emerging opportunistic pathogen

Rhodococcus equi: An emerging opportunistic pathogen
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DOI:
10.1016/0966-842x(96)81502-2
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发表时间:
1996-01-01
影响因子:
15.9
通讯作者:
Hondalus, MK
Hondalus, MK
中科院分区:
生物学1区
文献类型:
--
作者:
Mosser, DM;Hondalus, MK

文献摘要

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马红球菌正在成为免疫功能低下人群,特别是艾滋病患者肺炎的一种病因。与分枝杆菌一样,R.马被肺泡巨噬细胞吞噬并在其中复制。最近的工作开始阐明这种机会致病菌的细胞和分子生物学以及宿主对它的免疫反应。
Rhodococcus equi is emerging as a cause of pneumonia in immunocompromised people, especially those with AIDS. Like mycobacteria, R. equi is phagocytosed by alveolar macrophages and replicates within them. Recent work is beginning to elucidate the cell and molecular biology of this opportunistic pathogen and the host immune response to it.