Behavioral inhibition in preschool children at risk is a specific predictor of middle childhood social anxiety: A five-year follow-up

Behavioral inhibition in preschool children at risk is a specific predictor of middle childhood social anxiety: A five-year follow-up
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DOI:
10.1097/01.dbp.0000268559.34463.d0
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发表时间:
2007-06-01
影响因子:
2.4
通讯作者:
Rosenbaum, Jerrold F.
Rosenbaum, Jerrold F.
中科院分区:
医学4区
文献类型:
--
作者:
Hirshfeld-Becker, Dina R.;Biederman, Joseph;Rosenbaum, Jerrold F.

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目的:对陌生事物的行为抑制(BI)是指在面对陌生人或陌生环境时表现出恐惧、沉默或克制的气质倾向。它被假设为焦虑症的危险因素。在这项前瞻性纵向研究中,我们比较了在学龄前评估BI的儿童在童年中期的精神结果。方法:基线样本包括284名年龄在21个月到6岁之间的儿童,包括有焦虑风险的后代(父母患有惊恐障碍和/或重度抑郁症的儿童)和没有情绪或重度焦虑障碍的父母的比较后代。使用特定年龄的实验室方案对他们进行了BI评估。我们在5年随访时对215名儿童(76.5%)进行了重新评估,平均年龄为9.6岁,使用结构化诊断访谈。结果:ELL特异性预测社交焦虑的发生。抑制与非抑制儿童的终身社交焦虑(DSM-IV社交恐惧症或DSM-III-R回避障碍)发生率分别为28%和14%(比值比[OR] = 2.37; 95%置信区间[CI]:1.10 - 5.10)。在基线时未受影响的儿童中,BI可显著预测社交恐惧症的新发(抑制型与非抑制型儿童中分别为22.2%和8.0%)(OR = 3.15,95%CI:1.16-8.57)。没有其他焦虑症与BI相关。结论:BI似乎是一个气质的前因,随后在童年中期的社交焦虑。应监测BI儿童的社交焦虑症状,并可能是预防性认知行为策略的良好候选人。
Objective: Behavioral inhibition (BI) to the unfamiliar represents the temperamental tendency to exhibit fearfulness, reticence, or restraint when faced with unfamiliar people or situations. it has been hypothesized to be a risk factor for anxiety disorders. in this prospective longitudinal study, we compared the psychiatric outcomes in middle childhood of children evaluated at preschool age for BI. Method: The baseline sample consisted of 284 children ages 21 months to 6 years, including offspring at risk for anxiety (children of parents with panic disorder and/or major depression) and comparison offspring of parents without mood or major anxiety disorders. They had been assessed for BI using age-specific laboratory protocols. We reassessed 215 of the children (76.5%) at 5-year follow-up at a mean age of 9.6 years using structured diagnostic interviews. Results: Ell specifically predicted onset of social anxiety. The rate of lifetime social anxiety (DSM-IV social phobia or DSM-III-R avoidant disorder) was 28% versus 14% (odds ratio [OR] = 2.37; 95% confidence interval [CI]: 1.10 -5.10) in inhibited versus noninhibited children. BI significantly predicted new onset of social phobia among children unaffected at baseline (22.2% vs 8.0% in inhibited versus noninhibited children (OR = 3.15, 95% CI: 1.16-8.57). No other anxiety disorders were associated with Bl. Conclusion: BI appears to be a temperamental antecedent to subsequent social anxiety in middle childhood. Children presenting with BI should be monitored for symptoms of social anxiety and may be good candidates for preventive cognitive behavioral strategies.