Goldfish bipolar cells and axon terminal patterns: a Golgi study.
Goldfish bipolar cells and axon terminal patterns: a Golgi study.
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金鱼双极细胞和轴突末端模式：高尔基体研究。
DOI：
10.1002/cne.903290204
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Yazulla,S
中科院分区：
文献类型：
--
作者：
Sherry,DM;Yazulla,S
为了更好地了解视网膜内丛状层(IPL)内双极细胞的组织结构，对高尔基体染色的金鱼双极细胞的形态和轴突终末排列进行了观察。鉴定出15种形态双极细胞类型，代表两种主要细胞类型：接受视杆和视锥感光细胞输入的混合输入细胞，以及仅接受视锥细胞输入的视锥双极细胞。混合输入双极电池由六种类型组成，其中包括两种新类型，其特点是体型和端子较大。混合输入双极细胞的终末严格终止于IPL的椎弓下动脉内。锥体双极细胞由9个亚型组成，其中包括7个新亚型，特征是小的胞体和沿轴突长度的1至4个小的终末球茎，每个终末球沿IPL具有特征的终末深度。锥体双极细胞系统在IPL内具有复杂的终末多层组织，但保持了关于亚板和亚板的高度解剖对称性。锥体双极细胞可分为三类：在亚板内终止的细胞，在解剖上对称的对应物终止在亚板内；在两个亚板内具有解剖上相似终末的细胞；在亚板和亚板内没有解剖对称对应物或在解剖上不同的终末的细胞。根据双极细胞的终末排列，我们认为每种双极细胞类型在IPL中可能有一组独特的突触靶点，几种双极细胞类型可能参与了IPL中多个水平上的功能对等电路。©1993 Wiley-Liss，Inc.
The morphology and axon terminal arrangement of Golgi stained goldfish bipolar cells were examined to understand better the organization of bipolar cells in the inner plexiform layer (IPL) of the retina. Fifteen morphological bipolar cell types were identified, representing two major cell classes: mixed input cells that receive input from rod and cone photoreceptors, and cone bipolar cells that receive input from cones only. Mixed input bipolar cells comprised six types, including two new types, characterized by large somas and terminals. The terminals of mixed input bipolar cells terminated strictly within sublaminaaorbof the IPL. Cone bipolar cells comprised nine subtypes, including seven new types, characterized by small somas and from one to four small terminal bulbs along the length of the axon, each having a characteristic termination depth in the IPL. The cone bipolar cell system had a complex multilaminar organization of terminals in the IPL, but maintained a high degree of anatomical symmetry about sublaminaaandb. Cone bipolar cells could be divided into three groups: cells terminating within sublaminaaand having an anatomically symmetrical counterpart terminating in sublaminab; cells with anatomically similar terminals in both sublaminaaandb; and cells having no anatomically symmetrical counterpart or having anatomically dissimilar terminals in sublaminaaandb. Based on bipolar cell terminal arrangement, we suggest that each bipolar cell type probably has a unique set of synaptic targets in the IPL, and that several bipolar cell types may be involved in functionally equivalent circuits at more than one level in the IPL. © 1993 Wiley‐Liss, Inc.