The effect of a 12-week combinational exercise program on CD4 count and mental health among HIV infected women: A randomized control trial
The effect of a 12-week combinational exercise program on CD4 count and mental health among HIV infected women: A randomized control trial
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DOI：
10.1016/j.jesf.2018.02.001
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发表时间：
2018-04-01
影响因子：
2.8
通讯作者：
AminiLari, Mahmood
中科院分区：
文献类型：
--
作者：
Dianatinasab, Mostafa;Fararouei, Mohammad;AminiLari, Mahmood
背景/目的：关于运动对HIV阳性患者免疫功能的影响，存在相互矛盾的结果。运动也可以有益于患者的心理功能。本研究的目的是确定为期12周的有氧和抗阻运动训练计划对女性HIV+ patients.Methods的心理健康和CD 4计数的影响：这项临床试验是在2013年9月至12月之间进行的。从240名自愿咨询和治疗中心（VCT）的HIV阳性妇女中仔细选择了40名参与者（年龄范围20-40岁），并随机分配到运动组（80分钟的有氧和力量训练，同时接受VCT的常规服务）（n = 20）或对照组（仅接受VCT的常规服务）（n = 20）。为了评估他们的心理健康状况，所有参与者都完成了GHQ 28问卷。在基线和12周干预结束时采集血液样本测量CD 4和T细胞计数。结果：从40名HIV感染妇女的样本中，分析了30名参与者[实验组（14）和对照组（16）]的数据（参与率75%）。结果表明，干预后，两组间CD 4细胞计数差异有统计学意义（P = 0.01）。在心理健康方面，干预后运动组的焦虑、社会功能、抑郁及心理健康总分均较对照组有显著改善（P < 0.001）。结论：运动训练可作为改善HIV感染妇女心理健康状况的保健服务内容。未检测到对CD 4计数的影响。(C)2018中国运动生理与体适能学者学会。出版社：Elsevier（新加坡）Pte Ltd
Background/objective: There are conflicting results regarding the effects of exercise on immune function of HIV positive patients. Exercise can also be beneficial to psychological functioning of the patients. The purpose of this study was to determine the impact of a 12-week aerobic and resistance exercise training program on mental health and CD4 counts among female HIV+ patients.Methods: This clinical trial was conducted between September and December 2013. Forty participants (women age range 20-40) were carefully selected from 240 HIV-positive women referred to Voluntary Counseling and Treatment Center (VCT) and randomly assigned to either exercise (80 min of aerobic and strength training while receiving the VCT's routine services) group (n = 20) or control (received the VCT's routine services only) group (n = 20). To assess their mental health status, all participants completed GHQ28 questionnaire. Blood samples were collected to measure CD4 and T-cell counts at baseline and at the end of the 12-week intervention.Results: From a sample of 40 women with HIV infection, the data of 30 participants [experimental group (14) and control group (16)] were analyzed (participation rate 75%). The results indicated that after the intervention program, a significant difference in CD4 cell counts was found between the two groups (P = 0.01). With regard to mental health, after performing intervention, significant improvement in all subscales including anxiety disorder, social function, depression and mental health's total score was observed in the exercise compared to the control groups (P < 0.001).Conclusion: Exercise training can be included in health care services in order to improve the mental health status of women with HIV infection. No effect on CD4 count was detected. (C) 2018 The Society of Chinese Scholars on Exercise Physiology and Fitness. Published by Elsevier (Singapore) Pte Ltd.