Malaria risk factors in Amerindian children in French Guiana
Malaria risk factors in Amerindian children in French Guiana
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DOI：
10.4269/ajtmh.2007.76.619
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发表时间：
2007-04-01
影响因子：
3.3
通讯作者：
Carme, Bernard
中科院分区：
文献类型：
--
作者：
Hustache, Sarah;Nacher, Mathieu;Carme, Bernard
疟疾是法属圭亚那的一个主要公共卫生问题。这项研究是在法属圭亚那东部的一个美洲印第安人村庄Camopi的1-5岁儿童中进行的。采用Kaplan-Meier方法和考克斯模型对疟疾的医疗、环境和行为预测因素进行了研究。变量包括清理房屋周围的植被（清除50-75%的危害比[HR] = 0.62，95%置信区间[CI] = 0.43-0.88;清除> 75%的危害比[HR]= 0.5，95% CI = 0.31-0.81）;家到河的距离（HR = 0.56，对于20和40米之间的距离，95% CI = 0.37-0.85，HR = 0.72，对于40和80米之间的距离，95% CI = 0.47-1.09，HR = 0.52，80 ~ 120 m的95%CI = 0.28-0.94，> 120 m的HR = 0.5，95%CI 0.30-0.86）相对于< 20 m的距离;家中居住者的数量（7名乘员的HR 1.54，95%CI = 0.98-2.44; 8-11名乘员的HR = 1.9，95%CI = 1.29-2.81;> 11名乘员的HR = 2.03，95%CI = 1.27-3.23）;服装（相对于穿传统卡林贝的儿童，穿西式服装的儿童的HR = 0.64，95%CI = 0.46-0.90）和种族（相对于Emerillon儿童，Wayampi儿童患疟疾的风险较低：HR = 0.55，95%CI = 0.40-0.80）。家附近的环境与疟疾密切相关。这表明，简单实用的保护措施在卡莫皮是有用的。
Malaria is a major public health problem in French Guiana. This study was conducted in children < 1-5 years of age in Camopi, an Amerindian village in eastern French Guiana. Medical, environmental, and behavioral predictive factors of malaria were studied using the Kaplan-Meier method and Cox modeling. Variables included were clearing vegetation around the home (hazard ratio [HR] = 0.62, 95% confidence interval [CI] = 0.43-0.88 for 50-75% cleared and HR = 0.5, 95% Cl = 0.31-0.81 for > 75% cleared) relative to homes surrounded by vegetation; distance of a home from a river (HR = 0.56, 95 % CI = 0.37-0.85 for distances between 20 and 40 meters, HR = 0.72, 95 % CI = 0.47-1.09 for distances between 40 and 80 meters, HR = 0.52, 95% Cl = 0.28-0.94 for distances between 80 and 120 meters, and HR = 0.5, 95% Cl 0.30-0.86 for distances > 120 meters) relative to distances < 20 meters; the number of occupants in the home (HR 1.54, 95% CI = 0.98-2.44 for 7 occupants, HR = 1.9, 95% CI = 1.29-2.81 for 8-11 occupants, and HR = 2.03, 95% CI = 1.27-3.23 for > 11 occupants); clothing (HR = 0.64, 95% Cl = 0.46-0.90 for children wearing western-style clothes relative to those wearing the traditional kalimbe), and ethnicity (Wayampi children had a lower hazard of malaria relative to Emerillon children: HR = 0.55, 95% CI = 0.40-0.80). The environment near the home was strongly associated with malaria. This suggests that simple pragmatic protection measures would be useful in Camopi.