Nitrogen-Doped Graphene and Its Application in Electrochemical Biosensing
Nitrogen-Doped Graphene and Its Application in Electrochemical Biosensing
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氮掺杂石墨烯及其在电化学生物传感中的应用
DOI：
10.1021/nn100315s
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发表时间：
2010-04-01
期刊：
影响因子：
17.1
通讯作者：
Lin, Yuehe
中科院分区：
文献类型：
--
作者：
Wang, Ying;Shao, Yuyan;Lin, Yuehe
化学掺杂是对基质材料进行本质改性的一种有效方法。其中，氮掺杂对碳材料的电子性质起着至关重要的调节作用。最近，石墨烯作为一种真正的二维碳材料，在生物电子学和生物传感器方面显示出了令人着迷的应用。本文报道了一种利用氮等离子体处理化学方法合成的石墨烯来制备氮掺杂石墨烯的简便方法。同时，提出了一种可能的原理图，详细描述了N掺杂石墨烯的结构。通过控制曝光时间，可以调节主体石墨烯中的N含量，范围为0.11~1.35%。此外，所制备的N掺杂石墨烯对过氧化氢的还原表现出很高的电催化活性，对葡萄糖氧化酶表现出快速的直接电子转移动力学。在干扰存在的情况下，N掺杂石墨烯进一步用于浓度低至0.01 mM的葡萄糖生物传感。
Chemical doping with foreign atoms is an effective method to intrinsically modify the properties of host materials. Among them, nitrogen doping plays a critical role in regulating the electronic properties of carbon materials. Recently, graphene, as a true two-dimensional carbon material, has shown fascinating applications in bioelectronics and biosensors. In this paper, we report a facile strategy to prepare N-doped graphene by using nitrogen plasma treatment of graphene synthesized via a chemical method. Meanwhile, a possible schematic diagram has been proposed to detail the structure of N-doped graphene. By controlling the exposure time, the N percentage in host graphene can be regulated, ranging from 0.11 to 1.35%. Moreover, the as-prepared N-doped graphene has displayed high electrocatalytic activity for reduction of hydrogen peroxide and fast direct electron transfer kinetics for glucose oxidase. The N-doped graphene has further been used for glucose biosensing with concentrations as low as 0.01 mM in the presence of interferences.