“Prenatal Stress, Glucocorticoids and the Programming of the Brain” (2001), by Leonie Welberg and Jonathan Seckl
“Prenatal Stress, Glucocorticoids and the Programming of the Brain” (2001), by Leonie Welberg and Jonathan Seckl
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发表时间：
2020
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通讯作者：
J. Seckl
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作者：
J. Seckl
2001年，研究人员Leonie Welberg和Jonathan Seckl发表了文献综述《产前应激、糖皮质激素和大脑的编程》，其中他们报告了产前应激对胎儿大脑发育的影响。胎儿[5]在子宫中或在子宫中经历产前压力。在讨论产前应激的影响时，作者描述了产前编程，即早期环境经历在一生中永久性地改变生物结构和功能。在《产前应激、糖皮质激素和大脑的程序设计》一书中，Welberg和Seckl从动物和人类研究中提供了许多潜在的生物学解释，以解释程序设计中涉及的潜在机制，这些机制有助于确定宫内压力如何影响胎儿大脑发育。
In 2001, researchers Leonie Welberg and Jonathan Seckl published the literature review “Prenatal Stress, Glucocorticoids, and the Programming of the Brain,” in which they report on the effects of prenatal stress on the development of the fetal brain. The fetus [5] experiences prenatal stress while in the womb [6], or in utero. In discussing the effects of prenatal stress, the authors describe prenatal programming, which is when early environmental experiences permanently alter biological structure and function throughout life. Throughout “Prenatal Stress, Glucocorticoids and the Programming of the Brain,” Welberg and Seckl provide a number of potential biological explanations, derived from both animal and human studies, to explain the underlying mechanisms involved in programming, which helped establish how in utero stress can affect fetal brain development.