Expression of Scavenger Receptor-BI and Low-Density Lipoprotein Receptor and Differential Use of Lipoproteins to Support Early Steroidogenesis in Luteinizing Macaque Granulosa Cells
Expression of Scavenger Receptor-BI and Low-Density Lipoprotein Receptor and Differential Use of Lipoproteins to Support Early Steroidogenesis in Luteinizing Macaque Granulosa Cells
复制标题
DOI：
10.1210/en.2008-0619
复制
发表时间：
2009-02-01
期刊：
影响因子：
4.8
通讯作者：
Chaffin, Charles L.
中科院分区：
文献类型：
--
作者：
Cherian-Shaw, Mary;Puttabyatappa, Muraly;Chaffin, Charles L.
人绒毛膜促性腺激素(HCG)刺激恒河猴接受控制性卵巢刺激后，孕酮合成迅速持续增加。脂蛋白作为孕酮合成底物的作用尚不清楚，人绒毛膜促性腺激素(HCG)后不久脂蛋白受体[极低密度脂蛋白受体(VLDLR)、低密度脂蛋白受体(LDLR)和清道夫受体-BI(SR-BI)]的表达也尚不清楚。
An ovulatory hCG stimulus to rhesus macaques undergoing controlled ovarian stimulation protocols results in a rapid and sustained increase in progesterone synthesis. The use of lipoproteins as a substrate for progesterone synthesis remains unclear, and the expression of lipoprotein receptors [very-low-density lipoprotein receptor (VLDLR), low-density lipoprotein receptor (LDLR), and scavenger receptor-BI (SR-BI)] soon after human chorionic gonadotropin (hCG) (