Cytoarchitecture of the human superior olivary complex: Nuclei of the trapezoid body and posterior tier
Cytoarchitecture of the human superior olivary complex: Nuclei of the trapezoid body and posterior tier
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DOI：
10.1016/j.heares.2008.04.010
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发表时间：
2008-07-01
期刊：
影响因子：
2.8
通讯作者：
Kulesza, Randy J., Jr.
中科院分区：
文献类型：
--
作者：
Kulesza, Randy J., Jr.
上级橄榄复合体（SOC）是位于尾侧脑干被盖的一簇核团，形成听觉通路的重要组成部分。SOC包括两个主要核团，内侧和外侧上级橄榄（分别为MSO和LSO），在声源定位中具有明确的作用。围绕主核的是一些橄榄周核（PON），它们在哺乳动物物种之间差异很大，但在听觉的多个方面发挥作用。尽管已在许多实验室动物中研究了PON，但尚未在人类中描绘出这些细胞核。本研究的主要目标是，根据骨髓结构，位置，神经元形态和细胞结构，定义PON内的人类SOC和提供这些核内的神经元数量的估计。从12个人脑干的研究结果提供了证据，为6个形态不同的细胞群：三个内的梯形体和三个沿着后面的方面的SOC。基于分析的人类组织染色的髓鞘，尼氏物质，或浸渍银，人PON出现在很大程度上同源的PON描述在其他低频听力动物。(C)2008 Elsevier B.V.保留所有权利。
The superior olivary complex (SOC) is a cluster of nuclei situated in the caudal brainstem tegmentum that forms an essential component of the auditory pathway. The SOC includes two principal nuclei, the medial and lateral superior olives (MSO and LSO respectively), that have clear roles in sound source localization. Surrounding the principal nuclei are a number of periolivary nuclei (PON) that vary significantly between mammalian species but function in multiple aspects of hearing. Although the PON have been studied in numerous laboratory animals, these nuclei have not been delineated in human. The major goal of this study is to, based on myeloarchitecture, location, neuronal morphology and cytoarchitecture, define the PON within the human SOC and provide estimates of neuronal number within these nuclei. Results from the study of twelve human brainstems provide evidence for six morphologically distinct cell groups: three within the trapezoid body and three along the posterior aspect of the SOC. Based on the analysis of human tissue stained for myelin, Nissl substance, or impregnated with silver, the human PON appear largely homologous to the PON described in other low-frequency hearing animals. (C) 2008 Elsevier B.V. All rights reserved.