Surface modification of electrospun polycaprolactone microfibers by air plasma treatment: Effect of plasma power and treatment time
Surface modification of electrospun polycaprolactone microfibers by air plasma treatment: Effect of plasma power and treatment time
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DOI：
10.1016/j.eurpolymj.2016.09.060
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发表时间：
2016-11-01
影响因子：
6
通讯作者：
Cervantes-Uc, J. M.
中科院分区：
文献类型：
--
作者：
Can-Herrera, L. A.;Avila-Ortega, A.;Cervantes-Uc, J. M.
聚己内酯 (PCL) 是一种经 FDA 批准用于医疗器械的生物相容性聚合物，但通常被认为是疏水性材料。为了改善这一缺点，通过在三个功率水平（10、20、30 W）和三个放电时间（1、3、5 分钟）下的空气等离子体处理对电纺 PCL 微纤维进行表面改性。使用光谱和显微技术，如傅里叶变换红外光谱 (FTIR)、能量色散 X 射线光谱 (EDX)、X 射线光电子能谱 (XPS)、扫描电子显微镜 (SEM) 和原子力显微镜 (AFM) 来跟踪微纤维发生的变化；还测定了接触角和表面能，并通过邻甲苯胺蓝法（TBO）估算了羧基浓度。 SEM 和 AFM 图像表明，静电纺丝微纤维在处理后没有发生形态或形貌变化。在水中接触角减小，而在二碘甲烷中，空气等离子体处理后接触角增大。尽管 EDX 和 XPS 的结果显示处理后含氧物质和 O/C 比有所增加，但 FTIR 光谱并未显示等离子体处理改变了微纤维的表面化学成分的证据。 XPS 光谱中 O1s 信号的解卷积表明，羧基 (COOH) 随着处理时间的延长而增加，这一点通过 TBO 方法得到了证实和量化。通过 XPS 测量的 COOH 基团的百分比与 TBO 分析中获得的浓度相关。 (C) 2016 Elsevier Ltd. 保留所有权利。
Polycaprolactone (PCL) is a biocompatible polymer approved by the FDA for using in medical devices but it is generally considered as hydrophobic material. In order to improve this drawback, electrospun PCL microfibers were superficially modified by air plasma treatments at three power levels (10, 20, 30 W) and three discharge times (1, 3, 5 min). The changes undergone by the microfibers were followed using spectroscopic and microscopic techniques such as Fourier Transform Infrared Spectroscopy (FTIR), Energy dispersive X-ray spectroscopy (EDX), X-ray Photoelectron Spectroscopy (XPS), Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM); contact angle and surface energy were also determined and the concentration of carboxylic groups was estimated by means of the o-toluidine blue method (TBO). SEM and AFM images demonstrated that the electrospun microfibers did not suffer morphological or topographical changes after the treatment. The contact angle in water diminished, whereas with diiodomethane, it increased after air plasma treatment. FTIR spectra did not show evidence that the plasma treatment modified the surface chemical composition of the microfibers, although the results from EDX and XPS showed an increase in oxygen-containing species and in the O/C ratio after treatment. Deconvolution of the O1s signals in the XPS spectra demonstrated that the carboxylic groups (COOH) increase with treatment time, which was confirmed and quantified with the TBO method. The percentage of the COOH groups measure by XPS was correlated with the concentration obtained in the TBO analysis. (C) 2016 Elsevier Ltd. All rights reserved.