Black Phosphorus Nanoparticle Labels for Immunoassays via Hydrogen Evolution Reaction Mediation.
Black Phosphorus Nanoparticle Labels for Immunoassays via Hydrogen Evolution Reaction Mediation.
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DOI：
10.1021/acs.analchem.6b02422
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发表时间：
2016-10
影响因子：
7.4
通讯作者：
Carmen C. Mayorga-Martinez;Naziah Mohamad Latiff;Alex Yong Sheng Eng;Zdenek Sofer;M. Pumera
中科院分区：
文献类型：
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作者：
Carmen C. Mayorga-Martinez;Naziah Mohamad Latiff;Alex Yong Sheng Eng;Zdenek Sofer;M. Pumera
黑磷是一种新兴的层状材料。其纳米颗粒显示出增加的带隙相比，散装材料，它们通常是通过超声波处理宏观黑磷晶体。在这里，我们制造黑磷纳米粒子（BP NPs）的溶液为基础的电化学剥离与双极电极，诱导相反的电位上的黑磷大颗粒的相对两端，从而导致其分解成纳米粒子。与黑磷大颗粒相比，BP纳米颗粒对析氢反应具有更强的催化作用。我们利用黑磷纳米颗粒作为电催化标签在竞争性免疫测定兔免疫球蛋白G（IgG）的检测。检测信号是通过BP NP的纳米冲击，然后HER催化产生的。
Black phosphorus is an emerging layered material. Its nanoparticles show an increased bandgap when compared to bulk materials and they are typically fabricated by ultrasonication of macroscopic black phosphorus crystals. Here we fabricate black phosphorus nanoparticles (BP NPs) by solution based electrochemical exfoliation with bipolar electrodes, which induces opposite potentials on the opposite ends of black phosphorus macroparticles thereby leading to its decomposition into nanoparticles. BP NPs have enhanced catalytic effect on the hydrogen evolution reaction (HER) relative to black phosphorus macroparticles. We utilize black phosphorus nanoparticles as electrocatalytic tags in a competitive immunoassay for rabbit immunoglobulin G (IgG) detection. The detection signal is produced via nanoimpacts of the BP NPs followed by HER catalysis.