Evidence Supporting Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 While Presymptomatic or Asymptomatic.
Evidence Supporting Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 While Presymptomatic or Asymptomatic.
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DOI：
10.3201/eid2607.201595
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发表时间：
2020-07-01
影响因子：
11.8
通讯作者：
Sobel, Jeremy
中科院分区：
文献类型：
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作者：
Furukawa, Nathan W;Brooks, John T;Sobel, Jeremy
最近的流行病学、病毒学和建模报告支持严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）从症状前（症状发作前检测到SARS-CoV-2）或无症状（检测到SARS-CoV-2但从未出现症状）人群传播的可能性。SARS-CoV-2在没有症状的情况下传播，加强了预防SARS-CoV-2由尽管具有传染性但可能不表现出疾病的感染者传播的措施的价值。关键的知识差距包括无症状和有症状的SARS-CoV-2感染的相对发生率，预防无症状传播的公共卫生干预措施，以及无症状的SARS-CoV-2感染是否赋予保护性免疫力的问题。
Recent epidemiologic, virologic, and modeling reports support the possibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from persons who are presymptomatic (SARS-CoV-2 detected before symptom onset) or asymptomatic (SARS-CoV-2 detected but symptoms never develop). SARS-CoV-2 transmission in the absence of symptoms reinforces the value of measures that prevent the spread of SARS-CoV-2 by infected persons who may not exhibit illness despite being infectious. Critical knowledge gaps include the relative incidence of asymptomatic and symptomatic SARS-CoV-2 infection, the public health interventions that prevent asymptomatic transmission, and the question of whether asymptomatic SARS-CoV-2 infection confers protective immunity.