Effects of a palatinose-based liquid diet (Inslow) on glycemic control and the second-meal effect in healthy men
Effects of a palatinose-based liquid diet (Inslow) on glycemic control and the second-meal effect in healthy men
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DOI：
10.1016/j.metabol.2006.09.005
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发表时间：
2007-01-01
影响因子：
9.8
通讯作者：
Takeda, Eiji
中科院分区：
文献类型：
--
作者：
Arai, Hidekazu;Mizuno, Akira;Takeda, Eiji
餐后高血糖可导致长期高胰岛素血症，是2型糖尿病的危险因素。低血糖指数的食物会减缓餐后血糖和胰岛素水平的快速上升。我们在此研究了一种新的，帕拉金糖为基础的液体饮食（Inslow，明治乳制品，东京，日本）对餐后血糖和胰岛素水平的影响，并对7名健康男性的底物氧化率。此外，为了检查Inslow对第二餐效应的影响，我们量化了受试者在摄入含有Inslow或对照配方的早餐后长达7小时的餐后血糖，胰岛素和游离脂肪酸水平，然后在5小时后吃标准午餐。我们的结果表明，Inslow负荷后30分钟的血糖和胰岛素水平峰值低于对照配方奶负荷后。Inslow组的餐后脂肪氧化率高于对照配方奶粉组（P
Postprandial hyperglycemia induces prolonged hyperinsulinemia, which is a risk factor for type 2 diabetes rnellitus. Foods with a low glycemic index blunt the rapid rise in postprandial plasma glucose and insulin levels. We herein investigated the effects of a novel, palatinose-based liquid diet (Inslow, Meiji Dairy Products, Tokyo, Japan) on postprandial plasma glucose and insulin levels and on the rate of substrate oxidation in 7 healthy men. Furthermore, to examine the effects of Inslow on the second-meal effect, we quantified our subjects' postprandial plasma glucose, insulin, and free fatty acid levels for up to 7 hours after they ingested a breakfast containing Inslow or control formula, followed by a standard lunch 5 hours later. Our results showed that peak plasma glucose and insulin levels 30 minutes after Inslow loading were lower than after control formula, loading. Postprandial fat oxidation rates in the Inslow group were higher than in the control formula group (P