Association between neonatal intensive care unit medication safety practices, adverse events, and death.
Association between neonatal intensive care unit medication safety practices, adverse events, and death.
复制标题
新生儿重症监护病房用药安全实践、不良事件和死亡之间的关联。
DOI：
10.1038/s41372-020-00857-y
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Greenberg,RachelG
中科院分区：
文献类型：
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作者：
Miller,LauraE;DeRienzo,Chris;Smith,PBrian;Bose,Carl;Clark,ReeseH;Cotten,CMichael;Benjamin,DanielK;Hornik,ChiD;Greenberg,RachelG
确定新生儿重症监护室（NICU）用药安全实践、实验室不良事件（lab-AE）和死亡之间的关联。研究设计我们将2016年Pediatrix NICU用药安全实践调查数据与2014-2016年婴儿数据相结合。我们根据使用的安全措施数量（≤5，6-7和8-10）对NICU进行分组，并使用logistic regressions.ResultsOf 94个NICU，17%使用≤5种药物安全措施，51%使用6-7，32%使用8-10。NICU与更多的安全措施没有差异，在实验室不良事件或death.ConclusionIn这个队列中，使用更多的药物安全的做法是不相关的实验室不良事件或减少死亡。
ObjectiveDetermine the associations between neonatal intensive care unit (NICU) medication safety practices, laboratory-based adverse events (lab-AEs), and death.Study designWe combined data from a 2016 survey of Pediatrix NICUs on use of medication safety practices with 2014–2016 infant data. We grouped NICUs based on the number of safety practices used (≤5, 6–7, and 8–10) and evaluated the association between the number of safety practices used and lab-AEs and deaths using logistic regressions.ResultsOf the 94 NICUs included, 17% used ≤5 medication safety practices, 51% used 6–7, and 32% used 8–10. NICUs with more safety practices did not have a difference in lab-AEs or death.ConclusionIn this cohort, the use of more medication safety practices was not associated with fewer lab-AEs or decreased death.