Thiourea inhibitors of herpes viruses.: Part 2:: N-benzyl-N′-arylthiourea inhibitors of CMV
Thiourea inhibitors of herpes viruses.: Part 2:: N-benzyl-N′-arylthiourea inhibitors of CMV
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DOI：
10.1016/j.bmcl.2004.04.093
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发表时间：
2004-07-05
影响因子：
2.7
通讯作者：
DiGrandi, MJ
中科院分区：
文献类型：
--
作者：
Bloom, JD;Dushin, RG;DiGrandi, MJ
制备并评价了一系列具有改进的稳定性的高效巨细胞病毒（CMV）硫脲抑制剂。化合物29以0.2nM的IC 50抑制培养的HFF细胞中的病毒。(C)2004年由Elsevier Ltd.出版。
A series of highly potent thiourea inhibitors of cytomegalovirus (CMV) with improved stability properties was prepared and evaluated. Compound 29 inhibited the virus in cultured HFF cells with IC50 of 0.2 nM. (C) 2004 Published by Elsevier Ltd.