Control of mitochondrial dynamics by a fusogenic lipid.
Control of mitochondrial dynamics by a fusogenic lipid.
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通过融合脂质控制线粒体动力学。
DOI：
10.1016/j.tcb.2023.10.006
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发表时间：
2023
影响因子：
19
通讯作者：
Chan,DavidC
中科院分区：
文献类型：
--
作者：
Yang,Zheng;Chan,DavidC
线粒体融合使线粒体群体之间能够相互合作，对线粒体的功能至关重要。线粒体表面的磷脂酸(PA)在线粒体融合中起着关键作用。苏等人最近的一项研究。结果表明，核苷二磷酸(NDP)激酶NME3识别PA并介导其对线粒体动力学的影响。
Mitochondrial fusion enables cooperation between the mitochondrial population and is critical for mitochondrial function. Phosphatidic acid (PA) on the mitochondrial surface has a key role in mitochondrial fusion. A recent study by Su et al. shows that the nucleoside diphosphate (NDP) kinase NME3 recognizes PA and mediates its effects on mitochondrial dynamics.