Transposable element detection from whole genome sequence data.
Transposable element detection from whole genome sequence data.
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DOI：
10.1186/s13100-015-0055-3
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发表时间：
2015
期刊：
影响因子：
4.9
通讯作者：
Ewing AD
中科院分区：
文献类型：
--
作者：
Ewing AD
在过去的 5 年里，可用于从全基因组序列数据中检测转座元件插入的软件工具的数量一直在稳步增加。其中一些方法具有适合特定用例的独特功能，但通常它们遵循一个或多个通用方法。在此，根据转座元件生物学和全基因组测序的现状对检测和过滤方法进行了回顾。我们证明，当前最先进的方法仍然不能产生高度一致的结果，并为协助转座元件检测方法的未来发展提供资源。本文的在线版本 (doi:10.1186/s13100-015-0055-3) 包含补充材料，可供授权用户使用。
The number of software tools available for detecting transposable element insertions from whole genome sequence data has been increasing steadily throughout the last ~5 years. Some of these methods have unique features suiting them for particular use cases, but in general they follow one or more of a common set of approaches. Here, detection and filtering approaches are reviewed in the light of transposable element biology and the current state of whole genome sequencing. We demonstrate that the current state-of-the-art methods still do not produce highly concordant results and provide resources to assist future development in transposable element detection methods. The online version of this article (doi:10.1186/s13100-015-0055-3) contains supplementary material, which is available to authorized users.
影响因子：
14.9
作者：
Lucier JF;Perreault J;Noël JF;Boire G;Perreault JP
通讯作者：
Perreault JP