Postexercise depression of motor evoked potentials: a measure of central nervous system fatigue
Postexercise depression of motor evoked potentials: a measure of central nervous system fatigue
复制标题
运动后运动诱发电位抑制：中枢神经系统疲劳的衡量标准
作者：
J. Brasil;Á. Pascual;J. Valls;Á. Cammarota;L. Cohen;M. Hallett
随意肌肉努力的疲劳是一个复杂的和多方面的现象。周围神经系统的组成部分，包括收缩器和神经肌肉接头的疲劳，已经得到了很好的研究。中枢神经系统也会疲劳，但由于缺乏客观的方法，研究一直滞后。经颅磁刺激是一种相对较新的技术，可用于评估从运动皮层到α-运动神经元的中枢神经系统兴奋性。在6名正常志愿者（包括4名研究者）中，运动后经颅磁刺激诱发的运动诱发电位幅度短暂下降，表明中枢神经系统运动通路疲劳。振幅的降低与疲劳感有关。这种现象的机制是运动皮层中运动指令的产生效率明显降低。
Fatigue of voluntary muscular effort is a complex and multifaceted phenomenon. Fatigue of peripheral nervous system components, including the contractile apparatus and the neuromuscular junction, has been well studied. Central nervous system components also fatigue, but studies have lagged for want of objective methods. Transcranial magnetic stimulation is a relatively new technique that can be used to assess central nervous system excitability from the motor cortex to the alpha-motoneuron. In six normal volunteers, including four of the investigators, the amplitudes of motor evoked potentials elicited by transcranial magnetic stimulation were transiently decreased after exercise, indicating fatigue of motor pathways in the central nervous system. The decrease in amplitude was associated with a feeling of fatigue. The mechanism of this phenomenon is apparently decreased efficiency in the generation of the motor command in the motor cortex.
影响因子：
2.5
作者：
BIGLANDRITCHIE, B;JOHANSSON, R;WOODS, JJ
通讯作者：
WOODS, JJ