Surface-plasmon-enhanced fluorescence from periodic quantum dot arrays through distance control using biomolecular linkers
Surface-plasmon-enhanced fluorescence from periodic quantum dot arrays through distance control using biomolecular linkers
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DOI：
10.1088/0957-4484/20/1/015305
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发表时间：
2009-01-07
期刊：
影响因子：
3.5
通讯作者：
Jen, Alex K-Y
中科院分区：
文献类型：
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作者：
Zin, Melvin T.;Leong, Kirsty;Jen, Alex K-Y
我们已经开发了一种蛋白质激活的策略来制造量子点（QD）纳米阵列，其中表面等离子体增强荧光增加了15倍。这种方法允许通过生物分子识别的方式对QD和金纳米阵列的集体行为组件进行横向（经由光刻限定的金纳米阵列）和垂直（经由QD-金属距离）的全面控制。具体而言，我们证明了等离子体共振金属纳米阵列的光谱调谐和蛋白质功能化的量子点的自组装，以逐步的方式与伴随的增量增加，通过生物素-链霉亲和素间隔单元从金属表面分离。
We have developed a protein-enabled strategy to fabricate quantum dot (QD) nanoarrays where up to a 15-fold increase in surface-plasmon-enhanced fluorescence has been achieved. This approach permits a comprehensive control both laterally (via lithographically defined gold nanoarrays) and vertically (via the QD-metal distance) of the collectively behaving assemblies of QDs and gold nanoarrays by way of biomolecular recognition. Specifically, we demonstrated the spectral tuning of plasmon resonant metal nanoarrays and self-assembly of protein-functionalized QDs in a stepwise fashion with a concomitant incremental increase in separation from the metal surface through biotin-streptavidin spacer units.