Etiological Factors and Symptom Triggers in Functional Motor Symptoms and Functional Seizures: A Pilot Investigation.
Etiological Factors and Symptom Triggers in Functional Motor Symptoms and Functional Seizures: A Pilot Investigation.
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功能性运动症状和功能性癫痫发作的病因和症状触发因素：一项试点调查。
DOI：
10.1176/appi.neuropsych.20230103
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发表时间：
2024
期刊：
影响因子：
--
通讯作者：
Millman LSM
中科院分区：
文献类型：
--
作者：
Millman LSM
这项研究检查了功能性运动症状（FMS）或功能性癫痫发作（FS）的病因和症状触发因素，并评估了与相关临床特征（即，17名患有FMS或FS的参与者和17名健康对照参与者进行了深入的临床访谈，并完成了评估不良生活事件、心理和身体症状、述情障碍、自闭症特征、疾病感知、健康相关生活质量（HRQoL）、结果患有FMS或FS的参与者认为各种原因的障碍，包括身体症状（65%），情绪问题（53%），不良生活事件（47%），与工作有关的因素（29%）。FMS和FS的触发因素包括体力活动或劳累（59%），压力和情绪（59%），感官体验（47%）和疲劳（41%）。与健康对照参与者相比，FMS或FS参与者在青春期报告了更多的不良事件，以及更高水平的述情障碍、躯体形式分离、心理分离（脱离、人格解体和现实解体）、焦虑、抑郁和身体症状。FMS或FS参与者的HRQoL比健康对照参与者更差，工作和社会功能受损。HRQoL评分和躯体形式分离，焦虑和不良生活事件之间呈负相关。结论FMS或FS的参与者报告了不同的生物心理社会病因和症状触发因素。持续的心理症状和终生不良经历与HRQoL较差相关。未来的研究将在更大样本的FMS或FS患者中检查这些因素，以更好地了解其共同和独特的病因基础。
ObjectiveThis study examined etiological factors and symptom triggers of functional motor symptoms (FMS) or functional seizures (FS) and assessed potential relationships with relevant clinical features (i.e., functional symptoms, quality of life, and general functioning).MethodsSeventeen participants with FMS or FS and 17 healthy control participants underwent an in-depth clinical interview and completed questionnaires assessing adverse life events, psychological and physical symptoms, alexithymia, autistic traits, illness perceptions, health-related quality of life (HRQoL), and work and social functioning.ResultsParticipants with FMS or FS perceived various causes of the disorder, including physical symptoms (65%), emotional problems (53%), adverse life events (47%), and work-related factors (29%). Triggers of FMS and FS included physical activity or exertion (59%), stress and emotions (59%), sensory experiences (47%), and fatigue (41%). Compared with healthy control participants, participants with FMS or FS reported more adverse events during adolescence and higher levels of alexithymia, somatoform dissociation, psychological dissociation (disengagement, depersonalization, and derealization), anxiety, depression, and physical symptoms. Participants with FMS or FS had worse HRQoL than healthy control participants and impaired work and social functioning. There were inverse associations between HRQoL scores and somatoform dissociation, anxiety, and adverse life events.ConclusionsParticipants with FMS or FS reported diverse biopsychosocial etiological factors and symptom triggers. Ongoing psychological symptoms and lifetime adverse experiences were associated with worse HRQoL. Future studies will examine these factors in larger samples of individuals with FMS or FS to better understand their shared and distinct etiological underpinnings.
心因性非癫痫发作：病因、诊断和治疗
DOI：
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发表时间：
2014
期刊：
影响因子：
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作者：
M. Oto;M. Reuber
通讯作者：
M. Reuber
GAD-7 在成人分离性癫痫发作中的表现
DOI：
--
发表时间：
2022
期刊：
Seizure
影响因子：
--
作者：
L. Goldstein;S. Vitoratou;J. Stone;T. Chalder;M. B. Lopez;A. Carson;M. Reuber
通讯作者：
M. Reuber
功能性运动症状和功能性癫痫发作的客观和主观神经认知功能：初步发现
影响因子：
2.2
作者：
Susannah Pick;L. Millman;Yiqing Sun;Eleanor Short;B. Stanton;Joel S Winston;Mitul A. Mehta;T. Nicholson;A. Reinders;Anthony S David;Mark J. Edwards;Laura H Goldstein;M. Hotopf;T. Chalder
通讯作者：
T. Chalder