Gene copy number: learning to count past two.

Gene copy number: learning to count past two.
复制标题

基因拷贝数:学习数过去二。

DOI:
10.1038/nm1009-1127
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发表时间:
2009
期刊:
影响因子:
82.9
通讯作者:
Kaslow,RichardA
Kaslow,RichardA
中科院分区:
医学1区
文献类型:
--
作者:
Shrestha,Sadeep;Tang,Jianming;Kaslow,RichardA

文献摘要

相似文献

已发现编码HIV共受体配体的基因的拷贝数影响对HIV感染和AIDS进展的易感性。新的研究对这一结论提出了质疑。这些研究受到原始发现作者的质疑,并强调了准确测量基因拷贝数的固有困难(第1110-1112,1112-1115,1115-1117和1117-1120页)。
The number of copies of the gene encoding a ligand for an HIV co-receptor have been found to influence the susceptibility to HIV infection and AIDS progression. New studies dispute this conclusion. The studies are contested by the authors of the original findings, and highlight the inherent difficulties in accurately measuring gene copy numbers (pages 1110–1112, 1112–1115, 1115–1117 and 1117–1120).