Population-based cohorts of the 50s and over: a summary of worldwide previous and ongoing studies for research on health in ageing.
Population-based cohorts of the 50s and over: a summary of worldwide previous and ongoing studies for research on health in ageing.
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DOI：
10.1007/s10433-006-0022-4
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发表时间：
2006-03-01
影响因子：
3.8
通讯作者：
Santos-Eggimann, Brigitte
中科院分区：
文献类型：
--
作者：
Seematter-Bagnoud, Laurence;Santos-Eggimann, Brigitte
由于大多数国家面临人口老龄化，了解成功老龄化和病理性老龄化是研究的重点。需要对中年开始的衰老过程进行纵向研究，以建立因果关系和有效关系。这项对文献的系统回顾旨在确定基于社区的大型纵向研究，要么专门包括老年人，要么跟踪从中年人（入组时 50 岁以上）到死亡的人，并选出了 72 项队列研究。所选研究的设计特点表明，大多数研究是在北美或北欧进行的，大多数包括两种性别，且随访期往往少于10年。许多队列关注心血管健康、认知能力下降或骨质疏松症。通常收集的变量包括社会人口统计、慢性疾病和功能状态的自我报告数据，以及认知、人体测量和身体表现的测量数据。大约 60% 的研究采集了生物样本，三分之一的研究还进行了基因分析。这篇综述总结了基于大量老年人群的设计和内容的信息，并提供了可以检索更多数据的宝贵背景。
As most countries face the ageing of their population, understanding successful and pathologic ageing is a research priority. Longitudinal studies examining the ageing process from middle-age are required to establish causal and valid relationships. This systematic review of the literature aimed at identifying large community-based longitudinal studies either including exclusively elderly people or following people from middle-age (50+ years at enrolment) to death, and resulted in a selection of 72 cohort studies. Design features of selected studies show that most were conducted in North America or Northern Europe, most included both genders, and follow-up period was often less than 10years. Many cohorts focused on cardiovascular health, cognitive decline or osteoporosis. Usually collected variables comprise of self-reported data on socio-demographics, chronic diseases and functional status, as well as measures of cognition, anthropometrics and physical performances. Biological samples were taken in about 60% of the studies, and a third also undertook genetic analyses. This review summarises information on design and content of large population-based cohorts of older persons, and represents a valuable background from which additional data may be retrieved.