A novel L-Lactate sensor based on enzyme electrode modified with ZnO nanoparticles and multiwall carbon nanotubes
A novel L-Lactate sensor based on enzyme electrode modified with ZnO nanoparticles and multiwall carbon nanotubes
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DOI：
10.1016/j.jelechem.2011.06.024
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发表时间：
2010-11
期刊：
影响因子：
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通讯作者：
Y. Wang;Y. Bao;L. Lou;J. Li;W. Du;Z. Zhu;H. Peng;J.Z. Zhu
中科院分区：
文献类型：
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作者：
Y. Wang;Y. Bao;L. Lou;J. Li;W. Du;Z. Zhu;H. Peng;J.Z. Zhu
基于多壁碳纳米管（MWCNTs）和纳米氧化锌（ZnO）的协同作用，研制了一种高灵敏度、高稳定性的L-乳酸传感器。该复合材料独特的层状结构（PDDA/LOD/ZnO/MWCNTs）为保持LOD的生物活性和防止酶分子泄漏提供了良好的微环境。因此，该生物传感器具有良好的分析性能，包括高灵敏度和高选择性和令人满意的稳定性，以安培法测定L-乳酸。结果表明，所提出的PDDA/LOD/ZnO/MWCNTs薄膜是固定LOD酶以制造生物传感器的有吸引力的基质。
A highly sensitive and stable L-Lactate sensor based on the synergic action of multi-wall carbon nanotube (MWCNTs) and ZnO nanoparticles has been developed. The unique sandwich-like layer structure (PDDA/LOD/ZnO/MWCNTs) provides a favorable microenvironment to keep the bioactivity of LOD and prevent enzyme molecule leakage. Therefore, the proposed L-Lactate biosensor exhibited good analytical performances including high sensitivity and selectivity with satisfactory stability to amperometric determination of L-Lactate. The results indicated that the proposed PDDA/LOD/ZnO/MWCNTs film was an attractive matrix for the immobilization of LOD enzymes to fabricate biosensors.