Reducing fetal deaths in multiple births: optimal birthweights and gestational ages for infants of twin and triplet births.
Reducing fetal deaths in multiple births: optimal birthweights and gestational ages for infants of twin and triplet births.
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减少多胞胎胎儿死亡：双胞胎和三胞胎婴儿的最佳出生体重和胎龄。
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发表时间：
1996
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通讯作者：
Barbara Luke
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作者：
Barbara Luke
本研究的目的是确定与双胞胎和三胞胎的最低胎儿死亡率相关的出生体重和胎龄。研究设计是对1983-88年间美国所有活产和胎儿死亡的人群进行分析。按出生体重和胎龄分类，比较双胎和三胎与单胎的胎儿死亡率，并在每一个多胎中，以相对风险+/-95%Cls的最低比率与所有其他比率进行比较。在3700-4000 g和40-41周时，单胎的每1,000例妊娠的总体胎儿死亡率与最低胎儿死亡率分别为4.3与0.9;双胎在2500-2800 g和36-37周时分别为15.5与3.3;三胎在34-35周时分别为21.0与5.2。超过这些多胎特异性的最低范围，胎儿死亡的风险增加，双胞胎多于单胞胎，三胞胎最多。总之，在多特异性的理想范围内，出生体重和胎龄的达到可以使胎儿死亡率降低75-80%。
The objective of this study was to determine the birthweight and gestational age associated with the lowest fetal mortality for twins and triplets. The study design was a population-based analysis of all live births and fetal deaths in the US between 1983-88. Fetal mortality was compared by categories of birthweight and gestational age, for twins and triplets versus singletons, and within each plurality by the lowest rate compared to all other rates as relative risks +/- 95% Cls. The overall versus lowest fetal death rate per 1,000 conceptions for singletons was 4.3 versus 0.9 at 3700-4000 g and 40-41 weeks; for twins, 15.5 versus 3.3 at 2500-2800 g and 36-37 weeks; and for triplets, 21.0 versus 5.2 at 1900-2200 g at 34-35 weeks. Beyond these plurality-specific lowest ranges, the risk of fetal death increased, more for twins than singletons, and most for triplets. To conclude, fetal death rates can be reduced by 75-80% with attainment of birthweight and gestational age within a plurality-specific ideal range.