MONSTIR II: a 32-channel, multispectral, time-resolved optical tomography system for neonatal brain imaging.

MONSTIR II: a 32-channel, multispectral, time-resolved optical tomography system for neonatal brain imaging.
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DOI:
10.1063/1.4875593
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发表时间:
2014-05
期刊:
The Review of scientific instruments
影响因子:
--
通讯作者:
R. Cooper;Elliott Magee;N. Everdell;S. Magazov;M. Varela;D. Airantzis;A. Gibson;J. Hebden
R. Cooper;Elliott Magee;N. Everdell;S. Magazov;M. Varela;D. Airantzis;A. Gibson;J. Hebden
中科院分区:
其他
文献类型:
--
作者:
R. Cooper;Elliott Magee;N. Everdell;S. Magazov;M. Varela;D. Airantzis;A. Gibson;J. Hebden

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我们详细介绍了第二代UCL时间分辨光学层析成像系统,称为MONSTIR II的设计,施工和性能。该系统主要用于新生儿大脑的研究,采用32根光源光纤,顺序传输650至900 nm之间任何四种波长的皮秒光脉冲。32个探测器通道各自包含独立的光电倍增管和时间相关的光子计数电子器件,其允许以高时间分辨率测量每个源和每个探测器位置之间的光子渡越时间。该系统的响应时间,时间稳定性,串扰和光谱特性的报告。MONSTIR II的有效性通过对简单体模进行多光谱成像来证明。
We detail the design, construction and performance of the second generation UCL time-resolved optical tomography system, known as MONSTIR II. Intended primarily for the study of the newborn brain, the system employs 32 source fibres that sequentially transmit picosecond pulses of light at any four wavelengths between 650 and 900 nm. The 32 detector channels each contain an independent photo-multiplier tube and temporally correlated photon-counting electronics that allow the photon transit time between each source and each detector position to be measured with high temporal resolution. The system's response time, temporal stability, cross-talk, and spectral characteristics are reported. The efficacy of MONSTIR II is demonstrated by performing multi-spectral imaging of a simple phantom.