Burden of mood symptoms and disorders in implantable cardioverter defibrillator patients: a systematic review and meta-analysis of 39 954 patients.
Burden of mood symptoms and disorders in implantable cardioverter defibrillator patients: a systematic review and meta-analysis of 39 954 patients.
复制标题
DOI：
10.1093/europace/euad130
复制
发表时间：
2023-06-02
期刊：
影响因子：
6.1
通讯作者：
Keage, Hannah A. D.
中科院分区：
文献类型：
--
作者：
Ghezzi, Erica S.;Sharman, Rhianna L. S.;Selvanayagam, Joseph B.;Psaltis, Peter J.;Sanders, Prashanthan;Astley, Jack M.;Knayfati, Sara;Batra, Vrinda;Keage, Hannah A. D.
植入式心律转复除颤器(ICD)可防止心脏性猝死。焦虑、抑郁和创伤后应激障碍(PTSD)是被低估的症状。我们的目标是系统地综合情绪障碍和症状严重程度的患病率估计，以及ICD前后的干预。与对照组以及ICD患者的适应症(主症与继发性)、性别、休克状态和时间进行比较。从开始到2022年8月31日，无限制地搜索了数据库(Medline、SqucINFO、PubMed和Embase)；确定了4661篇文章，其中109篇(39954名患者)符合标准。随机效应Meta分析显示，在ICD患者中，临床相关焦虑发生率为22.58%(95%可信区间为18.26-26.91%)，而抑郁发生率为15.42%(95%可信区间为11.90%-18.94%)。创伤后应激障碍发生率为12.43%(95%可信区间为6.90~17.96%)。与适应症组相比，比率没有变化。经历电击的ICD患者更易发生临床相关的焦虑和抑郁[焦虑优势比(OR)=3.92(95%可信区间1.67~9.19)；抑郁优势比OR=1.87(95%可信区间1.34~2.59)]。植入后女性的焦虑症状高于男性[赫奇斯的g=0.39(95%可信区间0.15~0.62)]。植入后前5个月抑郁症状减轻[Hedge‘s g=0.13(95%CI 0.03~0.23)]，6个月后焦虑症状减轻[Hedge’s g=0.07(95%CI 0~0.14)]。抑郁和焦虑在ICD患者中非常普遍，特别是在那些经历电击的患者中。尤其值得关注的是ICD植入后创伤后应激障碍的流行。作为常规护理的一部分，应为ICD患者及其伴侣提供心理评估、监测和治疗。
Implantable cardioverter defibrillators (ICDs) prevent sudden cardiac death. Anxiety, depression, and post-traumatic stress disorder (PTSD) are underappreciated symptoms. We aimed to systematically synthesize prevalence estimates of mood disorders and symptom severities, pre- and post-ICD insertions. Comparisons were made with control groups, as well as within ICD patients by indication (primary vs. secondary), sex, shock status, and over time. Databases (Medline, PsycINFO, PubMed, and Embase) were searched without limits from inception to 31 August 2022; 4661 articles were identified, 109 (39 954 patients) of which met criteria. Random-effects meta-analyses revealed clinically relevant anxiety in 22.58% (95%CI 18.26–26.91%) of ICD patients across all timepoints following insertion and depression in 15.42% (95%CI 11.90–18.94%). Post-traumatic stress disorder was seen in 12.43% (95%CI 6.90–17.96%). Rates did not vary relative to indication group. Clinically relevant anxiety and depression were more likely in ICD patients who experienced shocks [anxiety odds ratio (OR) = 3.92 (95%CI 1.67–9.19); depression OR = 1.87 (95%CI 1.34–2.59)]. Higher symptoms of anxiety were seen in females than males post-insertion [Hedges’ g = 0.39 (95%CI 0.15–0.62)]. Depression symptoms decreased in the first 5 months post-insertion [Hedges’ g = 0.13 (95%CI 0.03–0.23)] and anxiety symptoms after 6 months [Hedges’ g = 0.07 (95%CI 0–0.14)]. Depression and anxiety are highly prevalent in ICD patients, especially in those who experience shocks. Of particular concern is the prevalence of PTSD following ICD implantation. Psychological assessment, monitoring, and therapy should be offered to ICD patients and their partners as part of routine care.
登录
查看更多内容
影响因子：
3.7
作者：
Edmondson D;Richardson S;Falzon L;Davidson KW;Mills MA;Neria Y
通讯作者：
Neria Y
影响因子：
37.8
作者：
Dunbar, Sandra B.;Dougherty, Cynthia M.;Zeigler, Vicki L.
通讯作者：
Zeigler, Vicki L.
影响因子：
158.5
作者：
Moss, AJ;Hall, WJ;Heo, M
通讯作者：
Heo, M
影响因子：
11.4
作者：
Blanch, Bianca;Lago, Luise P.;Ingles, Jodie
通讯作者：
Ingles, Jodie
DOI：
10.1097/hcr.0000000000000444
发表时间：
2020-03-01
影响因子：
3.8
作者：
Dougherty, Cynthia M.;Burr, Robert L.;Glenny, Robb W.
通讯作者：
Glenny, Robb W.