Cancer Facts & Figures 2021

Cancer Facts & Figures 2021
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2010
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2020年,美国15至39岁的青少年和年轻人(AYAs)将有约89,500例新发癌症病例和9,270例癌症死亡(表S1)。这些患者通常与年轻或老年患者人群分组,这掩盖了癌症分布,肿瘤生物学和生存率的重要差异。例如,越来越多的证据表明,AYA中的几种类型的癌症在分子上与其他年龄组中发生的癌症不同,这表明该年龄组中癌症的发展方式可能存在差异,并且最有效地治疗。AYA更有可能在晚期被诊断出来,因为在这个年龄组中,由于癌症的罕见性而导致的诊断延迟,以及更高的未保险率和更高的侵袭性疾病的患病率。3,4 AYA患者也有长期和晚期影响的高风险,包括不孕症,性功能障碍,心脏问题和未来的癌症。
In 2020, there will be approximately 89,500 new cancer cases and 9,270 cancer deaths in adolescents and young adults (AYAs) ages 15 to 39 years in the United States (Table S1). These patients are often grouped with younger or older patient populations, which masks important differences in cancer distribution, tumor biology, and survivorship. For example, an increasing body of evidence indicates that several types of cancer in AYAs are molecularly distinct from those that occur in other age groups, suggesting possible differences in how cancers in this age group develop and are most effectively treated.1, 2 In addition, for some cancer types, AYAs are more likely to be diagnosed at a late stage because of both delays in diagnosis due to the rarity of cancer in this age group and higher uninsured rates and higher prevalence of aggressive disease.3, 4 AYA patients also have a high risk of long-term and late effects, including infertility, sexual dysfunction, heart problems, and future cancers.5-8