Inactivation of airborne viruses using a packed bed non-thermal plasma reactor
Inactivation of airborne viruses using a packed bed non-thermal plasma reactor
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DOI：
10.1088/1361-6463/ab1466
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发表时间：
2019-06-19
影响因子：
3.4
通讯作者：
Clack, H. L.
中科院分区：
文献类型：
--
作者：
Xia, T.;Kleinheksel, A.;Clack, H. L.
麻疹或严重急性呼吸系统综合症等空气传播传染病的爆发会引起公众的严重恐慌。在通风系统促进疾病传播给人类或动物的情况下，需要在施加最小压差的同时提供有效保护的控制措施。在本研究中，在气流中的病毒气溶胶进行非热等离子体（NTP）暴露在填充床介质阻挡放电反应器。NTP处理之前和之后的噬菌斑测定的比较发现，随着施加电压的增加，雾化的MS 2噬菌体的失活呈指数增加。在30 kV和170标准升/分钟的空气流速下，在整个反应器中实现了大于2.3 log的感染性病毒减少。该减少表示类似于2 log的失活的MS 2和类似于0.35 log在填充床中物理去除。将空气流速从170升/分钟增加到330升/分钟不会显著影响病毒灭活效果。基于活性炭的臭氧过滤器大大减少了残留臭氧，在某些情况下降低到背景水平，同时在170标准升/分钟的流速下将小于20 Pa的压差增加到填充床两侧的45 Pa压差。
Outbreaks of airborne infectious diseases such as measles or severe acute respiratory syndrome can cause significant public alarm. Where ventilation systems facilitate disease transmission to humans or animals, there exists a need for control measures that provide effective protection while imposing minimal pressure differential. In the present study, viral aerosols in an airstream were subjected to non-thermal plasma (NTP) exposure within a packed-bed dielectric barrier discharge reactor. Comparisons of plaque assays before and after NTP treatment found exponentially increasing inactivation of aerosolized MS2 phage with increasing applied voltage. At 30 kV and an air flow rate of 170 standard liters per minute, a greater than 2.3 log reduction of infective virus was achieved across the reactor. This reduction represented similar to 2 log of the MS2 inactivated and similar to 0.35 log physically removed in the packed bed. Increasing the air flow rate from 170 to 330 liters per minute did not significantly impact virus inactivation effectiveness. Activated carbon-based ozone filters greatly reduced residual ozone, in some cases down to background levels, while adding less than 20 Pa pressure differential to the 45 Pa differential pressure across the packed bed at the flow rate of 170 standard liters per minute.