Switchable Hydrophobic Valve for Controlled Microfluidic Processing
Switchable Hydrophobic Valve for Controlled Microfluidic Processing
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DOI：
10.1002/cphc.201501015
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发表时间：
2016-03-16
期刊：
影响因子：
2.9
通讯作者：
Suzuki, Hiroaki
中科院分区：
文献类型：
--
作者：
Biswas, Gokul Chandra;Watanabe, Takahiro;Suzuki, Hiroaki
提出了一种简单的微流控阀，该阀不需要任何运动部件，可以利用低功率电信号在多种不同材料的微通道中按需控制溶液流量。许多独立操作的阀门可以很容易地集成到复杂的微流体系统中。该阀由一个自组装的单层（SAM）组成，形成在一个直接并入微通道的铂电极上。正常开启的阀门由于电极表面的疏水性SAM而停止溶液流动。通过在电极上施加电位，溶液被允许通过阀门，由于还原性解吸，它可以去除SAM。阀门运行高度稳定，开关次数约为15次。该阀是理想的控制溶液操作集成微分析系统和自主微流体系统。
A simple microfluidic valve, without any moving parts, is presented that can control solution flow on demand in microchannels of many different materials using a low-power electric signal. Many independently operating valves can easily be integrated into complex microfluidic systems. The valve consists of a self-assembled monolayer (SAM) formed on a platinum electrode that is incorporated directly in the microchannel. The normally-on valve stops the solution flow due to a hydrophobic SAM on the electrode surface. The solution is allowed to pass the valve by applying a potential to the electrode, which removes the SAM due to reductive desorption. The valve operation is highly stable and has switching times of the order of 1s. The valve is ideal for controlled solution manipulation in integrated micro-analytical systems and autonomous microfluidic systems.