Changes in the presentation of newly diagnosed type 1 diabetes in children during the COVID-19 pandemic in a tertiary center in Southern Turkey
Changes in the presentation of newly diagnosed type 1 diabetes in children during the COVID-19 pandemic in a tertiary center in Southern Turkey
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DOI：
10.1515/jpem-2021-0287
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发表时间：
2021-10-01
影响因子：
1.4
通讯作者：
Yuksel, Bilgin
中科院分区：
文献类型：
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作者：
Dilek, Semine Ozdemir;Gurbuz, Fatih;Yuksel, Bilgin
目标：COVID-19大流行是一个全球性的健康问题，发病率和死亡率都很高。本研究旨在调查在大流行期间被诊断为1型糖尿病的患者，并通过与一年前的结果进行比较，评估大流行对这些患者临床结果的影响。研究方法：2019年至2021年期间诊断为1型糖尿病的患者被分为两组：大流行前诊断的患者和大流行期间诊断的患者。结果：新诊断的糖尿病病例数从大流行前的46例增加到大流行期间的74例。门诊诊断为糖尿病酮症酸中毒（DKA）的病例数从58.7%增加到91.9%。我们发现中度和重度DKA的发生率分别从18.5%和14.8%降至23.5%和22.1%。此外，与大流行前相比，大流行期间诊断的病例的平均HbA 1c较高，而平均碳酸氢盐较低（p=0.048和p
Objectives: The COVID-19 pandemic is a global health problem with high morbidity and mortality. This study aimed to investigate patients who were diagnosed with type 1 diabetes during the pandemic and evaluate the effect of the pandemic on the clinical findings of these patients by comparing them with findings from a year prior. Methods: Patients diagnosed with type 1 diabetes mellitus between 2019 and 2021 were separated into two groups: Patients diagnosed prepandemic and those diagnosed during the pandemic. Results: The number of newly diagnosed diabetes cases increased from 46 in the prepandemic period to 74 in the pandemic period. The number of cases diagnosed with diabetic ketoacidosis (DKA) in the clinic increased from 58.7 to 91.9%. We found that moderate and severe DKA rates from 18.5 and 14.8% to 23.5 and 22.1%, respectively. Besides, the average HbA1c was higher, while the average bicarbonate was lower in cases diagnosed during the pandemic period compared to the prepandemic period (p=0.048 and p