Body composition by DXA: tried and true?
Body composition by DXA: tried and true?
复制标题
DXA 身体成分：经过验证且正确吗？
DOI：
10.1249/00005768-199510000-00001
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发表时间：
1995
影响因子：
4.1
通讯作者：
Wendy M. Kohrt
中科院分区：
文献类型：
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作者：
Wendy M. Kohrt
双能X线骨密度仪（DXA）无疑是评估骨量的首选方法。最近几代DXA仪器还具有评估软组织质量的能力，从而提供身体组成的三室模型，即，骨矿物质、脂肪和无骨瘦体重。虽然水密度测定法长期以来一直被认为是评估身体组成的参考方法，但关于无脂肪物质成分恒定性的假设可能会影响其在某些人群中的有效性。由于DXA似乎不太依赖于关于生物一致性的假设，因此它可能比水密度测定法更有可能提供对人群身体组成的更准确评估，并且应将其视为参考方法。DXA已被证明可以提供身体成分的精确测量，但这些测量是否准确仍然存在疑问。DXA仪器制造商在校准、数据采集和数据分析方法方面的差异导致了有效性的不确定性。虽然DXA在成为评估身体成分的标准方法方面有很大的希望，并且已经被一些研究人员推广，但现有数据表明，这种认可还为时过早。
Dual-energy x-ray absorptiometry (DXA) is unquestionably the method of choice for the assessment of bone mass. Recent generations of DXA instruments also have the capability of assessing soft tissue mass, thereby providing a three-compartment model of body composition, i.e., bone mineral, fat, and bone-free lean masses. Although hydrodensitometry has long been considered the reference method of assessing body composition, assumptions regarding the constancy of the constituents of fat-free mass may compromise its validity in some populations. Because DXA appears to be less dependent on assumptions regarding biological consistency, it is possible that it has the potential to provide a more accurate assessment of body composition across populations than does hydrodensitometry, and that it should be considered the reference method. DXA has been shown to provide precise measures of body composition, but it remains questionable as to whether those measures are accurate. Contributing to the uncertainty regarding validity is the variability among manufacturers of DXA instruments in the methods of calibration, data acquisition, and data analysis. Although DXA holds great promise in becoming the criterion method of assessing body composition, and has been promoted as such by some investigators, available data indicate that this endorsement is premature.