QUANTIFICATION OF TRANSPULMONARY ECHOCONTRAST EFFECTS
QUANTIFICATION OF TRANSPULMONARY ECHOCONTRAST EFFECTS
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DOI：
10.1016/0301-5629(93)90100-3
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发表时间：
1993-01-01
影响因子：
2.9
通讯作者：
ROELANDT, JRTC
中科院分区：
文献类型：
--
作者：
DEJONG, N;TENCATE, FJ;ROELANDT, JRTC
在10名健康志愿者中，静脉注射递增剂量的Albunex（R）0.01-0.02和0.04 mL/kg体重后，研究了左心和右心的视频密度。左心室影像密度的增加总是低于右心室。可能的解释是由环境压力变化引起的气体扩散和由于肺毛细血管床的筛分效应引起的微球分布的变化。这些现象在体外进行了研究，并与临床观察结果一致。这些局限性限制了静脉注射后左心回声对比的定量评估。
Videodensity of left heart and right heart were studied after intravenous injection of increasing dosages of 0.01-0.02 and 0.04 mL/kg bodyweight of Albunex(R) in 10 healthy volunteers. The increase in videodensity in the left ventricle was always lower than in the right ventricle. Possible explanations are diffusion of gases caused by ambient pressures changes and change in microspheres distribution due to the sieving effect of the lung capillary bed. These phenomena were studied in vitro and were consistent with clinical observations. These limitations restrict a quantitative assessment of left heart echocontrast after intravenous injection.