A FORTRAN PROGRAM FOR THE CALCULATION AND ANALYSIS OF 2-LOCUS LINKAGE DISEQUILIBRIUM COEFFICIENTS
A FORTRAN PROGRAM FOR THE CALCULATION AND ANALYSIS OF 2-LOCUS LINKAGE DISEQUILIBRIUM COEFFICIENTS
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DOI：
10.1007/bf00305981
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发表时间：
1985-01-01
影响因子：
5.4
通讯作者：
KRAFSUR, ES
中科院分区：
文献类型：
--
作者：
BLACK, WC;KRAFSUR, ES
编制了一个FORTRAN程序，用于根据遗传类型数据计算复合连锁不平衡系数。卡方检验确定等位基因和基因座对计算的系数是否显著大于零。提供了一个子程序，它将连锁不平衡中的方差划分为子群体内和子群体之间的分量。对家蝇(Musca home ticaL.)自然亚群的等位酶数据进行了分析。以说明该程序的功能。
A FORTRAN program was written that calculates composite linkage disequilibrium coefficients from genotypic data. Chi-square tests determine whether coefficients calculated for allele and locus pairs are significantly greater than zero. A subroutine is provided that partitions the variance in linkage disequilibrium into within- and between-subpopulation components. Output obtained from analysis of allozyme data collected from natural subpopulations of the house fly (Musca domesticaL.) are included to illustrate features of the program.