Effects of selenium and vitamin E deficiencies on reproduction, growth, blood components, and tissue lesions in sheep fed purified diets.
Effects of selenium and vitamin E deficiencies on reproduction, growth, blood components, and tissue lesions in sheep fed purified diets.
复制标题
硒和维生素 E 缺乏对饲喂纯化饲料的绵羊的繁殖、生长、血液成分和组织损伤的影响。
DOI：
10.1093/jn/107.7.1288
复制
发表时间：
1977
期刊：
影响因子：
--
通讯作者：
J. Oldfield
中科院分区：
文献类型：
--
作者：
P. Whanger;P. Weswig;J. A. Schmitz;J. Oldfield
采用3个2 × 2析因试验，研究了硒和维生素E对绵羊白色肌病（WMD）发病率和血液成分的影响。在不接受维生素E或硒的组中，所有达到6周龄的羔羊都出现了WMD病变，而在+E - Se或-E + Se治疗组中只有少数羔羊出现了这些病变。血浆肌酸磷酸激酶，乳酸脱氢酶和谷草转氨酶的活性显着升高，羔羊接受没有维生素E或硒，而这些酶的活性在那些只接受硒不显着升高。+E - Se或+E + Se处理组血浆中酶活性维持在较低水平，表明单独维生素E比单独硒更有效地预防WMD。这些要素的代谢相互作用进行了讨论。
Three 2 X 2 factorial experiments were conducted with sheep fed purified diets to determine the effects of selenium and vitamin E on the incidence of white muscle disease (WMD) and blood components. All lambs reaching 6 weeks of age in the group receiving no vitamin E or selenium developed WMD lesions, whereas only a few lambs in either the +E - Se or -E + Se treatment groups developed these lesions. Plasma activities of creatine phosphokinase, lactic dehydrogenase and glutamic oxaloacetic transaminase were significantly elevated in lambs receiving no vitamin E or selenium, whereas these enzyme activities in those receiving only selenium were non-significantly elevated. The enzyme activities in plasma of those on the +E - Se or +E + Se treatments were maintained at low levels, suggesting vitamin E alone is more effective in preventing WMD than selenium alone. The metabolic interactions of these essentials are discussed.