Poverty-associated risk factors for wheezing in the first year of life in Honduras and El Salvador
Poverty-associated risk factors for wheezing in the first year of life in Honduras and El Salvador
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DOI：
10.1016/j.aller.2010.01.003
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发表时间：
2010-07-01
影响因子：
1.8
通讯作者：
Garcia-Marcos, L.
中科院分区：
文献类型：
--
作者：
Bueso, A.;Figueroa, M.;Garcia-Marcos, L.
背景资料：在发达国家已经研究了特别是在生命的第一年中喘息的风险因素，但来自发展中国家的信息非常稀缺。目前还没有专门针对贫困因素的研究。本研究的目的是确定与贫困有关的危险因素是否与洪都拉斯和萨尔瓦多婴儿出生后第一年的喘息有关。使用经过验证的问卷进行调查，在圣佩德罗苏拉大都会地区进行（洪都拉斯）和La Libertad（萨尔瓦多萨尔瓦多）的中心，婴儿在12个月大时参加预定的疫苗接种或健康儿童访问。实地工作人员向家长提供调查问卷，并在必要时帮助文盲。主要的结果变量是喘息在第一年的生活中，由parents.Results报告：共有1047名婴儿在萨尔瓦多萨尔瓦多和780在洪都拉斯被列入分析。第一年喘息的患病率在萨尔瓦多（41.2%）高于洪都拉斯（27.7%），定义为三次或三次以上发作的复发性喘息也是如此（18.4% vs. 11.7%）。喘息和反复喘息与家中未铺地板有关（对于任何喘息和复发性喘息，两个国家的总结优势比分别为1.55，p=0.036和1.72，p=0.054）;灰尘从街道进入（1.30，p=0.052和1.67，p=0.008）;生活在污染严重的地区（1.33，p=0.037和1.52，p=0.033）;以及家庭墙壁上有霉菌污渍（1.36，p=0.072和1.76，p=0.007）。此外，还发现，家庭人口增加和使用煤油作为烹饪燃料的关系不大。大学研究的母亲（0.34，p=0.046和0.32，p=0.022）和一个专业职业的父亲（0.34，p=0.046和0.26，p=0.047）与较低的risk.Conclusions：众所周知，在萨尔瓦多和洪都拉斯的喘息和反复喘息的患病率很高。在这些人群中，与贫困相关的因素与喘息和反复喘息的患病率较高相关，而母亲教育程度较高和父亲职业为保护因素。(C)2010年SEICAP。出版社：Elsevier Espana，S.L. All rights reserved.
Background: Risk factors for wheezing specifically during the first year of life have been studied in well-developed countries, but the information from developing countries is very scarce. There are no such studies focusing on factors derived from poverty. The aim of the present study was to determine if risk factors related to poverty are associated to wheezing during the first year of life in infants from Honduras and El Salvador.Methods: A survey, using a validated questionnaire, was carried out in the metropolitan area of San Pedro Sula (Honduras) and in La Libertad (El Salvador) in centres where infants attended for a scheduled vaccination shot or a healthy child visit at 12 months of age. Fieldworkers offered questionnaires to parents and helped the illiterate when necessary. The main outcome variable was wheezing during the first year of life, as reported by parents.Results: A total of 1047 infants in El Salvador and 780 in Honduras were included in the analysis. The prevalence of wheeze in the first year was higher in El Salvador (41.2%) than in Honduras (27.7%), as was recurrent wheezing defined as three or more episodes (18.4% vs. 11.7%). Wheezing and recurrent wheezing was associated to unpaved floor in the household (summary odds ratios for both countries 1.55, p=0.036 and 1.72, p=0.054 for any wheeze and recurrent wheezing, respectively); dust entering from streets (1.30, p=0.052 and 1.67, p=0.008); living in a heavily polluted area (1.33, p=0.037 and 1.52, p=0.033); and having mould stains on the household walls (1.36, p=0.072 and 1.76, p=0.007). Furthermore, marginal associations were found for additional person at home and use of kerosene as cooking fuel. University studies in the mother (0.34, p=0.046 and 0.32, p=0.022) and a professional occupation in the father (0.34, p=0.046 and 0.26, p=0.047) were associated to a lower risk.Conclusions: The prevalence of wheezing and recurrent wheezing is notoriously high in El Salvador and Honduras. In those populations factors related to poverty are associated to a higher prevalence of wheezing and recurrent wheezing, whereas higher maternal education and paternal professional occupation behave as protective factors. (C) 2010 SEICAP. Published by Elsevier Espana, S.L. All rights reserved.