Ultrasonography of ureteric abnormalities induced by Schistosoma haematobium infection before and after praziquantel treatment.
Ultrasonography of ureteric abnormalities induced by Schistosoma haematobium infection before and after praziquantel treatment.
复制标题
吡喹酮治疗前后埃及血吸虫感染引起的输尿管异常的超声检查。
DOI：
10.1111/j.1464-410x.1994.tb07110.x
复制
发表时间：
1994
期刊：
影响因子：
--
通讯作者：
J. Ehrich
中科院分区：
文献类型：
--
作者：
R. Kardorff;M. Traoré;E. Doehring;U. Vester;J. Ehrich
目的
描述埃及血吸虫感染所致输尿管病变的超声表现，并报告吡喹酮治疗前后马里流行社区此类病变的患病率。
受试者和方法
3个S.在马里的一个有血吸虫病流行的村庄，对这些村庄进行了超声波检查，以检测尿路发病率。检测尿液中的S。用于血尿。在大量吡喹酮治疗后1年进行了相同的随访研究。
结果
S. 3个村的血吸虫感染率分别为53%、72%和73%。超声检查显示输尿管扩张143例（15%）。其中20例，主要是儿童和青少年，输尿管壁增厚和不规则，远端输尿管梗阻直接可视化超声检查。在另外两个人的膀胱内，输尿管囊肿样外观的腔内结构被视为。这些改变以前都没有被描述为泌尿系疾病的超声特征。活跃的S. 22例患者中，21例出现嗜血杆菌感染，20例出现显微血尿。其中10例有明显的肾梗阻。治疗一年后，在104名曾有输尿管扩张的患者中，85%的患者复查时发现尿路完全正常。输尿管壁增厚或输尿管囊肿样病变在95%的受试者中消失。
结论
超声波在评价泌尿系统疾病中的作用得到证实。输尿管壁异常引起狭窄和输尿管囊肿样病变的口必须被视为进一步的超声特征，这种情况。该研究记录了儿童和青少年抗人尿激酶治疗后输尿管异常的良好可逆性，从而强调了对感染进行早期有效药物治疗的必要性。
OBJECTIVE
To describe the ultrasonographic appearance of ureteric lesions due to Schistosoma haematobium infection and to report prevalence rates of such lesions in endemic communities in Mali before and after praziquantel treatment.
SUBJECTS AND METHODS
The total population (n = 961) of three S. haematobium-endemic villages in Mali was examined ultrasonographically to detect urinary tract morbidity. Urine was tested for S. haematobium ova and for haematuria. An identical follow-up study was performed 1 year after mass treatment with praziquantel.
RESULTS
Prevalence rates of S. haematobium infection in the three villages were 53%, 72% and 73%. Ultrasonography revealed dilatation of the ureters in 143 subjects (15%). In 20 of these, mainly children and adolescents, thickening and irregularities of the ureteric wall with distal ureter obstruction were directly visualized on ultrasonography. Within the bladder of two others, an intraluminal structure of ureterocele-like appearance was seen. None of these alterations has been previously described as an ultrasonographic feature of schistosomal uropathy. Active S. haematobium infection and microhaematuria were found in 21 and 20 of these 22 subjects respectively. Significant renal obstruction was present in 10 of them. One year after treatment, an entirely normal urinary tract was found in 85% of 104 re-examined individuals who had had ureter dilatation. Ureteric wall thickening or ureterocele-like lesions had disappeared in 95% of subjects.
CONCLUSIONS
The role of ultrasound in the evaluation of schistosomal uropathy is confirmed. Ureteric wall abnormalities causing strictures and ureterocele-like lesions of the ostium must be regarded as further ultrasonographic features of this condition. The study documents the excellent reversibility of ureteric abnormalities after antischistosomal treatment in children and adolescents, thus emphasizing the need for early and efficient medical treatment of the infection.