Handedness and language cerebral lateralization
Handedness and language cerebral lateralization
复制标题
DOI：
10.1007/s00421-002-0652-y
复制
发表时间：
2002-08-01
影响因子：
3
通讯作者：
Basahi, J
中科院分区：
文献类型：
--
作者：
Khedr, EM;Hamed, E;Basahi, J
重复经颅磁刺激（rTMS）诱导偏侧言语停滞与大脑语言优势一致。不同利手的健康受试者的语言大脑优势的研究是有限的。使用聚焦磁线圈，我们研究了25名右利手和25名左撇子医学生的利手程度之间的一致性评价的斯坦利Coren分数和半球优势的语言确定rTMS。根据得分将他们分为24名强右利手，1名中度右利手，19名强左利手，3名中度左利手和3名左右手（均利手）。在强右利手的受试者中，左侧语言大脑优势占87.5%，双侧大脑代表占8.2%，右侧语言大脑优势占4.2%。在强左利手被试中，73.7%的被试具有左侧语言优势，15.8%的被试具有双侧语言优势，10.5%的被试具有右侧语言优势。在混合手的科目（中度右，左和ambiorus），双侧大脑的代表性，观察到在57%和左侧大脑语言优势43%。27例在运动阈的140%时发生言语停止，其余在较低强度时发生言语停止。语音偏侧的左侧大脑优势，在强烈的右，左撇子的科目，但双边的大脑代表性是经常在混合的手和右侧大脑优势很少发生。
Repetitive transcranial magnetic stimulation (rTMS) induces lateralized speech arrest consistent with cerebral dominance for language. Studies of language cerebral dominance in differently handed healthy subjects have been limited. Using a focal magnetic coil, we examined the degree of consistency between handedness as evaluated by the Stanley Coren Score and hemispheric dominance for language as determined by rTMS in 25 right- and 25 left-handed medical students. They were categorized according to the score into 24 strongly right-handed, I moderately right-handed, 19 strongly left-handed, 3 moderately left-handed and 3 ambidextrous (equally-handed). In the strongly right-handed subjects, left-sided language cerebral dominance was recorded in 87.5% of the subjects, and bilateral cerebral representation in 8.2%, and right-sided language cerebral dominance in 4.2%. In the strongly left-handed subjects, 73.7% had left-side language cerebral dominance, 15.8% had bilateral cerebral representation and 10.5% had right-side cerebral language dominance. In mixed handed subjects (moderately right, left and ambidextrous), bilateral cerebral representation was observed in 57% and left-side cerebral language dominance in 43%. There were 27 subjects who developed speech arrest at 140% of motor threshold, the others developed speech arrest at lower intensities. Speech lateralized to the left-side cerebral dominance in strongly right- and left-handed subjects, but bilateral cerebral representation was frequent in mixed handedness and right-sided cerebral dominance rarely occurred.