Improvement in depression scores after 1 hour of light therapy treatment in patients with seasonal affective disorder.
Improvement in depression scores after 1 hour of light therapy treatment in patients with seasonal affective disorder.
复制标题
DOI：
10.1097/nmd.0b013e31823e56ca
复制
发表时间：
2012-01
期刊：
影响因子：
--
通讯作者：
Postolache TT
中科院分区：
文献类型：
--
作者：
Reeves GM;Nijjar GV;Langenberg P;Johnson MA;Khabazghazvini B;Sleemi A;Vaswani D;Lapidus M;Manalai P;Tariq M;Acharya M;Cabassa J;Snitker S;Postolache TT
本研究的目的是探讨光疗法对季节性情感障碍患者抑郁情绪的快速影响。受试者接受1小时的强光治疗和1小时的安慰剂昏暗红光治疗，采用随机顺序交叉设计。在基线和每小时光照治疗后，使用两种自我报告抑郁量表（情绪状态-抑郁-沮丧[POMS-D]子量表和Beck抑郁量表II [BDI-II]）测量抑郁情绪。当对两个阶段的轻度影响进行分组时，BDI-II和POMS-D的自我报告抑郁评分分别降低了-1.3（p = 0.02）和-1.2（p = 0.02）。一个显着的，但适度的改善后，检测到一个单一的主动光会话。据我们所知，这是第一项研究，使用安慰剂对照设计，记录了抑郁症患者的临床样本的光治疗立即改善。
The purpose of this study was to investigate possible rapid effects of light therapy on depressed mood in patients with seasonal affective disorder. Participants received 1 hour of bright light therapy and 1 hour of placebo dim red light in a randomized order crossover design. Depressed mood was measured at baseline and after each hour of light treatment using two self-report depression scales (Profile of Mood States–Depression-Dejection [POMS-D] subscale and the Beck Depression Inventory II [BDI-II]). When light effects were grouped for the two sessions, there was significantly greater reduction in self-report depression scores by −1.3 (p = 0.02) on the BDI-II and −1.2 (p = 0.02) on the POMS-D. A significant but modest improvement was detected after a single active light session. This is the first study, to our knowledge, to document an immediate improvement with light treatment using a placebo-controlled design with a clinical sample of depressed individuals.